KUMAMOTO University

R

研究業績RESEARCH ACHIEVEMENTS

  1. Sugata K, Yasunaga J, Kinosada H, Mitobe Y, Furuta R, Mahgoub M, Onishi C, Nakashima K, Ohshima K, Matsuoka M.

    HTLV-1 Viral Factor HBZ Induces CCR4 to Promote T-cell Migration and Proliferation.

    Cancer Res. 2016 Sep 1;76(17):5068-79. doi: 10.1158/0008-5472.CAN-16-0361. Epub 2016 Jul 11. PMID: 27402079.

  2. Haji S, Kiyasu J, Choi I, Suehiro Y, Toyoda K, Tsuda M, Takamatsu A, Nakashima Y, Miyoshi H, Shiratsuchi M, Yamasaki S, Uike N, Abe Y.

    Administration of an anti-CC chemokine receptor 4 monoclonal antibody, mogamulizumab, before allogeneic bone marrow transplantation for adult T-cell leukemia/lymphoma.

    Bone Marrow Transplant. 2016 Mar;51(3):432-4. doi: 10.1038/bmt.2015.254. Epub 2015 Nov 2. PMID: 26524267.

  3. Maeshima AM, Taniguchi H, Toyoda K, Yamauchi N, Makita S, Fukuhara S, Munakata W, Maruyama D, Kobayashi Y, Tobinai K.

    Clinicopathological features of histological transformation from extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue to diffuse large B-cell lymphoma: an analysis of 467 patients.

    Br J Haematol. 2016 Sep;174(6):923-31. doi: 10.1111/bjh.14153. Epub 2016 Jul 27. PMID: 27460179.

  4. Moschetta M, Mishima Y, Kawano Y, Manier S, Paiva B, Palomera L, Aljawai Y, Calcinotto A, Unitt C, Sahin I, Sacco A, Glavey S, Shi J, Reagan MR, Prosper F, Bellone M, Chesi M, Bergsagel LP, Vacca A, Roccaro AM, Ghobrial IM.

    Targeting vasculogenesis to prevent progression in multiple myeloma.

    Leukemia. 2016 May;30(5):1103-15. doi: 10.1038/leu.2016.3. Epub 2016 Feb 3. PMID: 26859080.

  5. Roccaro AM, Sacco A, Shi J, Chiarini M, Perilla-Glen A, Manier S, Glavey S, Aljawai Y, Mishima Y, Kawano Y, Moschetta M, Correll M, Improgo MR, Brown JR, Imberti L, Rossi G, Castillo JJ, Treon SP, Freedman ML, Van Allen EM, Hide W, Hiller E, Rainville I, Ghobrial IM.

    Exome sequencing reveals recurrent germ line variants in patients with familial Waldenström macroglobulinemia.

    Blood. 2016 May 26;127(21):2598-606. doi: 10.1182/blood-2015-11-680199. Epub 2016 Feb 22. PMID: 26903547.

  6. Manier S, Kawano Y, Bianchi G, Roccaro AM, Ghobrial IM.

    Cell autonomous and microenvironmental regulation of tumor progression in precursor states of multiple myeloma.

    Curr Opin Hematol. 2016 Jul;23(4):426-33. doi: 10.1097/MOH.0000000000000259. PMID: 27101529.

  7. Glavey SV, Manier S, Sacco A, Salem K, Kawano Y, Bouyssou J, Ghobrial IM, Roccaro AM.

    Epigenetics in Multiple Myeloma.

    Cancer Treat Res. 2016;169:35-49. doi: 10.1007/978-3-319-40320-5_4. PMID: 27696257.

  8. Moschetta M, Kawano Y, Podar K.

    Targeting the Bone Marrow Microenvironment.

    Cancer Treat Res. 2016;169:63-102. doi: 10.1007/978-3-319-40320-5_6. PMID: 27696259.

  9. Inoue Y, Fuji S, Tanosaki R, Fukuda T.

    Pretransplant mogamulizumab against ATLL might increase the risk of acute GVHD and non-relapse mortality.

    Bone Marrow Transplant. 2016 May;51(5):725-7. doi: 10.1038/bmt.2015.315. Epub 2015 Dec 21. PMID: 26691420.

  10. Tanaka Y, Kurosawa S, Tajima K, Tanaka T, Ito R, Inoue Y, Okinaka K, Inamoto Y, Fuji S, Kim SW, Tanosaki R, Yamashita T, Fukuda T.

    Analysis of non-relapse mortality and causes of death over 15 years following allogeneic hematopoietic stem cell transplantation.

    Bone Marrow Transplant. 2016 Apr;51(4):553-9. doi: 10.1038/bmt.2015.330. Epub 2016 Jan 11. PMID: 26752142.

  11. Fuji S, Fujiwara H, Nakano N, Wake A, Inoue Y, Fukuda T, Hidaka M, Moriuchi Y, Miyamoto T, Uike N, Taguchi J, Eto T, Tomoyose T, Kondo T, Yamanoha A, Ichinohe T, Atsuta Y, Utsunomiya A; ATL Working Group of the Japan Society for Hematopoietic Cell Transplantation.

    Early application of related SCT might improve clinical outcome in adult T-cell leukemia/lymphoma.

    Bone Marrow Transplant. 2016 Feb;51(2):205-11. doi: 10.1038/bmt.2015.265. Epub 2015 Nov 2. PMID: 26524263.

  12. Kuriyama K, Fuji S, Inamoto Y, Tajima K, Tanaka T, Inoue Y, Ito R, Hayashi Y, Ito A, Kurosawa S, Kim SW, Yamashita T, Fukuda T.

    Impact of low-dose rabbit anti-thymocyte globulin in unrelated hematopoietic stem cell transplantation.

    Int J Hematol. 2016 Apr;103(4):453-60. doi: 10.1007/s12185-016-1947-9. Epub 2016 Feb 9. PMID: 26857285.

  13. Makita S, Fuji S, Takano K, Tanaka T, Inoue Y, Ito R, Ito A, Hayashi Y, Tajima K, Okinaka K, Kurosawa S, Kim SW, Yamashita T, Tanosaki R, Tobinai K, Fukuda T.

    Clinical Outcomes after Allogeneic Stem Cell Transplantation for Adult Lymphoblastic Lymphoma.

    J Clin Exp Hematop. 2016;56(1):28-33. doi: 10.3960/jslrt.56.28. PMID: 27334855; PMCID: PMC6144282.

  14. Fuji S, Inoue Y, Utsunomiya A, Moriuchi Y, Uchimaru K, Choi I, Otsuka E, Henzan H, Kato K, Tomoyose T, Yamamoto H, Kurosawa S, Matsuoka K, Yamaguchi T, Fukuda T.

    Pretransplantation Anti-CCR4 Antibody Mogamulizumab Against Adult T-Cell Leukemia/Lymphoma Is Associated With Significantly Increased Risks of Severe and Corticosteroid-Refractory Graft-Versus-Host Disease, Nonrelapse Mortality, and Overall Mortality.

    J Clin Oncol. 2016 Oct 1;34(28):3426-33. doi: 10.1200/JCO.2016.67.8250. Epub 2016 Aug 9. PMID: 27507878.

  15. Ghosh AK, Yashchuk S, Mizuno A, Chakraborty N, Agniswamy J, Wang YF, Aoki M, Gomez PM, Amano M, Weber IT, Mitsuya H.

    Design of gem-difluoro-bis-tetrahydrofuran as P2 ligand for HIV-1 protease inhibitors to improve brain penetration: synthesis, X-ray studies, and biological evaluation.

    ChemMedChem. 2015 Jan;10(1):107-15. doi: 10.1002/cmdc.201402358. Epub 2014 Oct 21. PMID: 25336073; PMCID: PMC4419590.

  16. Furuta RA, Ma G, Matsuoka M, Otani S, Matsukura H, Hirayama F.

    Reevaluation of confirmatory tests for human T-cell leukemia virus Type 1 using a luciferase immunoprecipitation system in blood donors.

    Transfusion. 2015 Apr;55(4):880-9. doi: 10.1111/trf.12911. Epub 2014 Nov 2. PMID: 25363675.

  17. Okazaki S, Mizuhara T, Shimura K, Murayama H, Ohno H, Oishi S, Matsuoka M, Fujii N.

    Identification of anti-HIV agents with a novel benzo[4,5]isothiazolo[2,3-a]pyrimidine scaffold.

    Bioorg Med Chem. 2015 Apr 1;23(7):1447-52. doi: 10.1016/j.bmc.2015.02.015. Epub 2015 Feb 16. PMID: 25744188.

  18. Suehiro Y, Hasegawa A, Iino T, Sasada A, Watanabe N, Matsuoka M, Takamori A, Tanosaki R, Utsunomiya A, Choi I, Fukuda T, Miura O, Takaishi S, Teshima T, Akashi K, Kannagi M, Uike N, Okamura J.

    Clinical outcomes of a novel therapeutic vaccine with Tax peptide-pulsed dendritic cells for adult T cell leukaemia/lymphoma in a pilot study.

    Br J Haematol. 2015 May;169(3):356-67. doi: 10.1111/bjh.13302. Epub 2015 Jan 22. PMID: 25612920.

  19. Kinpara S, Ito S, Takahata T, Saitoh Y, Hasegawa A, Kijiyama M, Utsunomiya A, Masuda M, Miyazaki Y, Matsuoka M, Nakamura M, Yamaoka S, Masuda T, Kannagi M.

    Involvement of double-stranded RNA-dependent protein kinase and antisense viral RNA in the constitutive NFκB activation in adult T-cell leukemia/lymphoma cells.

    Leukemia. 2015 Jun;29(6):1425-9. doi: 10.1038/leu.2015.1. Epub 2014 Jan 8. PMID: 25567137.

  20. Takachi T, Takahashi M, Takahashi-Yoshita M, Higuchi M, Obata M, Mishima Y, Okuda S, Tanaka Y, Matsuoka M, Saitoh A, Green PL, Fujii M.

    Human T-cell leukemia virus type 1 Tax oncoprotein represses the expression of the BCL11B tumor suppressor in T-cells.

    Cancer Sci. 2015 Apr;106(4):461-5. doi: 10.1111/cas.12618. Epub 2015 Mar 16. PMID: 25613934; PMCID: PMC4409891.

  21. Okazaki S, Oishi S, Mizuhara T, Shimura K, Murayama H, Ohno H, Matsuoka M, Fujii N.

    Investigations of possible prodrug structures for 2-(2-mercaptophenyl)tetrahydropyrimidines: reductive conversion from anti-HIV agents with pyrimidobenzothiazine and isothiazolopyrimidine scaffolds.

    Org Biomol Chem. 2015 Apr 28;13(16):4706-13. doi: 10.1039/c5ob00301f. PMID: 25800792.

  22. Ma G, Yasunaga J, Akari H, Matsuoka M.

    TCF1 and LEF1 act as T-cell intrinsic HTLV-1 antagonists by targeting Tax.

    Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):2216-21. doi: 10.1073/pnas.1419198112. Epub 2015 Feb 2. PMID: 25646419; PMCID: PMC4343127.

  23. Shimura K, Miyazato P, Oishi S, Fujii N, Matsuoka M.

    Impact of HIV-1 infection pathways on susceptibility to antiviral drugs and on virus spread.

    Virology. 2015 Oct;484:364-76. doi: 10.1016/j.virol.2015.06.029. Epub 2015 Jul 15. PMID: 26186575.

  24. Sato K, Kobayashi T, Misawa N, Yoshikawa R, Takeuchi JS, Miura T, Okamoto M, Yasunaga J, Matsuoka M, Ito M, Miyazawa T, Koyanagi Y.

    Experimental evaluation of the zoonotic infection potency of simian retrovirus type 4 using humanized mouse model.

    Sci Rep. 2015 Sep 14;5:14040. doi: 10.1038/srep14040. PMID: 26364986; PMCID: PMC4568461.

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