Fujimoto Y, Ueno S, Oda K, Gunda N, Shimomura Y, Nishimura Y, Yamaguchi A, Kuwano A, Ito Y, Baba Y, Nishigaki A, Michiwaki N, Uchino S, Kurogi K, Kawano Y, Matsuoka M, Saito H, Okuno Y, Jono H.

Relationship between serum bortezomib concentration and emergence of diarrhea in patients with multiple myeloma and/or AL amyloidosis.

Cancers 13(22),5674,2021. doi: 10.3390/cancers13225674.

https://pubmed.ncbi.nlm.nih.gov/34830830/

Ito A, Nakano N, Tanaka T, Fuji S, Makiyama J, Inoue Y, Choi I, Nakamae H, Nagafuji K, Takase K, Machida S, Takahashi T, Sawayama Y, Kamimura T, Kato K, Kawakita T, Ogata M, Sakai R, Shiratori S, Uchimaru K, Inamoto Y, Utsunomiya A, Fukuda T.

Improved survival of patients with aggressive ATL by increased use of allo-HCT: a prospective observational study.

Blood Adv 5(20):4156-66,2021. doi: 10.1182/bloodadvances.2021004932.

https://pubmed.ncbi.nlm.nih.gov/34500464/

Abdallah MG, Niibori-Nambu A, Morii M, Yokomizo T, Yokomizo T, Ideue T, Kubota S, Teoh VSI, Mok MMH, Wang CQ, Omar AA, Tokunaga K, Iwanaga E, Matsuoka M, Asou N, Nakagata N, Araki K, AboElenin M, Madboly SH, Sashida G, Osato M.

RUNX1-ETO (RUNX1-RUNX1T1) induces myeloid leukemia in mice in an age-dependent manner.

Leukemia 35(10):2983-2988,2021. doi: 10.1038/s41375-021-01268-4

https://pubmed.ncbi.nlm.nih.gov/34148054/

Ito S, Iwanaga M, Nosaka K, Imaizumi Y, Ishitsuka K, Amano M, Utsunomiya A, Tokura Y, Watanabe T, Uchimaru K, Tsukasaki K, Collaborative Investigators.

Epidemiology of adult T-cell leukemia-lymphoma in Japan: An updated analysis, 2012-2013.

Cancer Sci 112(10):4346-4354,2021. doi: 10.1111/cas.15097.

https://pubmed.ncbi.nlm.nih.gov/34355480/

Inoue Y, Okinaka K, Fuji S, Inamoto Y, Uchida N, Toya T, Ikegame K, Eto T, Ozawa Y, Iwato K, Kanda Y, Atsuta Y, Ogata M, Fukuda T, Transplant Complications Working Group of The Japan Society for Hematopoietic Cell Transplantation.

Severe acute graft-versus-host disease increases the incidence of blood stream infection and mortality after allogeneic hematopoietic cell transplantation: Japanese transplant registry study.

Bone Marrow Transplant 56(9):2125-36,2021.  doi: 10.1038/s41409-021-01291-0.

https://pubmed.ncbi.nlm.nih.gov/33875815/

Izutsu K, Ando K, Nishikori M, Shibayama H, Teshima T, Kuroda J, Kato K, Imaizumi Y, Nosaka K, Sakai R, Hojo S, Nakanishi T, Rai S.

Phase II study of tazemetostat for relapsed or refractory B-cell non-Hodgkin lymphoma with EZH2 mutation in Japan.

Cancer Sci 112(9):3627-3635,2021. doi: 10.1111/cas.15040.

https://pubmed.ncbi.nlm.nih.gov/34159682/

Ono A, Kitano Y, Imai K, Matsumoto T, Endo S, Tokunaga K, Hayashi H, Yamashita YI, Matsuoka M, Baba H.

A case of primary nonleukemic myeloid sarcoma of the spleen, successfully treated by surgery and hematopoietic stem cell transplantation.

Surg Case Rep 7(1):180,2021. doi: 10.1186/s40792-021-01257-w.

https://pubmed.ncbi.nlm.nih.gov/34379239/

Hosokawa K, Ishiyama K, Ikemoto T, Sugimori C, Noji H, Shichishima T, Obara N, Chiba S, Ninomiya H, Nguyen M.A.T, Shirasugi Y, Nakamura Y, Ando K, Ueda Y, Yonemura Y, Kawaguchi T, Nishimura J, Kanakura Y, Nakao S.

The clinical significance of PNH-phenotype cells accounting for < 0.01% of total granulocytes detected by the Clinical and Laboratory Standards Institute methods in patients with bone marrow failure.

Ann Hematol 100(8):1975-82,2021. doi: 10.1007/s00277-020-04314-w

https://pubmed.ncbi.nlm.nih.gov/33095337/

Toyoda K, Yasunaga JI, Choi I, Suehiro Y, Uike N, Okamura J, Matsuoka M.

The HTLV-1 proviral status is a potential prognostic biomarker for adult T-cell leukemia-lymphoma treated with allogeneic stem cell transplantation.

Bone Marrow Transplant 56(8):2027-2030,2021. doi: 10.1038/s41409-021-01311-z.

https://pubmed.ncbi.nlm.nih.gov/33927348/

Travis Chia, Tomofumi Nakamura, Masayuki Amano, Nobutoki Takamune, Masao Matsuoka, Hirotomo Nakata

A small molecule, ACAi-028, with anti-HIV-1 activity targets a novel hydrophobic pocket on HIV-1 capsid

Antimicrob Agents Chemother. 2021 Jul 6;AAC0103921. doi: 10.1128/AAC.01039-21. Online ahead of print.

https://pubmed.ncbi.nlm.nih.gov/34228546/

Kawakita T, Hirano T, Inoue Y, Irie Y, Sugitani H, Kubota A, Watanabe M, Ueno M, Mitsui N, Yamaguchi S, Inoue Y, Sakai T, Harada N, Matsuoka M, Hidaka M.

Feasibility of an intensified myeloablative conditioning regimen consisting of busulfan, fludarabine, cytarabine, and total body irradiation before single cord blood transplantation in elderly patients.

Int J Hematol 114(1):85-93,2021. doi: 10.1007/s12185-021-03131-9.

https://pubmed.ncbi.nlm.nih.gov/33740219/

Ohguchi H, Park PM, Wang T, Gryder BE, Ogiya D, Kurata K, Zhang X, Li D, Pei C, Masuda T, Johansson C, Wimalasena VK, Kim Y, Hino S, Usuki S, Kawano Y, Samur MK, Tai YT, Munshi NC, Matsuoka M, Ohtsuki S, Nakao M, Minami T, Lauberth S, Khan J, Oppermann U, Durbin AD, Anderson KC, Hideshima T, Qi J.

Lysine Demethylase 5A is Required for MYC Driven Transcription in Multiple Myeloma.

Blood Cancer Discov 2(4):370-387,2021. doi: 10.1158/2643-3230.BCD-20-0108.

https://pubmed.ncbi.nlm.nih.gov/34258103/

Sakata K, Kikuchi J, Emoto K, Kotaki T, Ota Y, Nishina N, Hanaoka H, Otomo K, Suzuki K, Kaneko Y, Takeuchi T.

Refractory IgG4-related Pleural Disease with Chylothorax: A Case Report and Literature Review.

Intern Med 60(13):2135-2143,2021.doi: 10.2169/internalmedicine.6313-20. Epub 2021 Feb 1.

https://pubmed.ncbi.nlm.nih.gov/33518567/

Hosen N, Yoshihara S, Takamatsu H, Ri M, Nagata Y, Kosugi H, Shimomura Y, Hanamura I, Fuji S, Minauchi K, Kuroda J, Suzuki R, Nishimura N, Uoshima N, Nakamae H, Kawano Y, Mizuno I, Gomyo H, Suzuki K, Ozaki S, Nakamura S, Imai Y, Kizaki M, Negoro E, Handa H, Iida S.

Expression of activated integrin β7 in multiple myeloma patients.

Int J Hematol 114(1):3-7,2021. doi: 10.1007/s12185-021-03162-2.

https://pubmed.ncbi.nlm.nih.gov/33999338/

Bianchi G, Czarnecki PG, Ho M, Roccaro AM, Sacco A, Kawano Y, Gulla A, Samur AA, Chen T, Wen K, Tai YT, Moscvin M, Wu X, Camci-Unal G, Da Via MC, Bolli N, Sewastianik T, Carrasco RD, Ghobrial IM, Anderson KC.

ROBO1 Promotes Homing, Dissemination, and Survival of Multiple Myeloma within the Bone Marrow Microenvironment.

Blood Cancer Discovery 2(4):338-353.2021. doi: 10.1158/2643-3230.BCD-20-0164. Epub 2021 Apr 10.

https://pubmed.ncbi.nlm.nih.gov/34238761/

Bellon M, Bialuk I, Galli V, Bai XT, Farre L, Bittencourt A, Marçais A, Petrus MN, Ratner L, Waldmann TA, Asnafi V, Gessain A, Matsuoka M, Franchini G, Hermine O, Watanabe T, Nicot C.

Germinal epimutation of Fragile Histidine Triad (FHIT) gene is associated with progression to acute and chronic adult T-cell leukemia diseases.

Mol Cancer 20(1):86,2021.  doi: 10.1186/s12943-021-01370-2.

https://pubmed.ncbi.nlm.nih.gov/34092254/

Yamauchi N, Maruyama D, Choi I, Atsuta Y, Sakai R, Miyashita K, Moriuchi Y, Tsujimura H, Kubota N, Yamamoto G, Igarashi T, Izutsu K, Yoshida S, Kojima K, Uchida T, Inoue Y, Tsukamoto N, Ohtsuka E, Suzuki S, Inaguma Y, Ichikawa S, Gomyo H, Ushijima Y, Nosaka K, Kurata M, Tanaka Y, Ueda R, Mizokami M, Kusumoto S.

Prophylactic antiviral therapy for HBsAg-positive patients with DLBCL treated with rituximab-containing chemotherapy.

Cancer Sci 112(5):1943-1954,2021. doi: 10.1111/cas.14846. Epub 2021 Mar 18.

https://pubmed.ncbi.nlm.nih.gov/33576088/

Shen YJ, Mishima Y, Shi J, Pistofidis RS, Redd R, Moschetta M, Manier S, Roccaro A, Sacco A, Tai YT, Mercier F, Kawano Y, Su N, Berrios B, Doench J, Root D, Michor F, Scadden D, Ghobrial IM.

Progression signature underlies clonal evolution and dissemination of multiple myeloma.

Blood 137(17):2360-2372,2021. doi: 10.1182/blood.2020005885.

https://pubmed.ncbi.nlm.nih.gov/33150374/

Ma G, Yasunaga JI, Shimura K,  Takemoto K, Watanabe M, Amano M, Nakata H, Liu B, Zuo X, and Matsuoka M.

Human retroviral antisense mRNAs are retained in the nuclei of infected cells for viral persistence

Proc Natl Acad Sci U S A.118(17):e2014783118,2021. doi: 10.1073/pnas.2014783118.

https://pubmed.ncbi.nlm.nih.gov/33875584/

Uekawa K, Kaku Y, Amadatsu T, Matsuzaki H, Ohmori Y, Kawano T, Hirata S, Yamaguchi T, Kosho T. & Mukasa A.

Intracranial and extracranial multiple arterial dissecting aneurysms in rheumatoid arthritis: A case report.

Interv Neuroradiol 27(2):212-218,2021. doi: 10.1177/1591019920965359.

https://pubmed.ncbi.nlm.nih.gov/33076745/

Ishihara A, Yamauchi T, Ikeda K, Fukuyoshi Y, Yokoyama T, Yonemura Y, Uchiba M, Matsui H.

Glycosylated ferritin as an improved marker for post-transfusion iron overload.

Int J Hematol 113(4): 537-546,2021. doi: 10.1007/s12185-020-03056-9. Epub 2021 Jan 5.

https://pubmed.ncbi.nlm.nih.gov/33400141/

Huang J, Gou H, Yao J, Yi K, Jin Z, Matsuoka M and Zhao T

The noncanonical role of EZH2 in cancer.

Cancer Sci 112(4):1376-1382. doi: 10.1111/cas.14840. Epub 2021 Feb 24.

https://pubmed.ncbi.nlm.nih.gov/33615636/

Penova M, Kawaguchi S, Yasunaga JI, Kawaguchi T, Sato T, Takahashi M, Shimizu M, Saito M, Tsukasaki K, Nakagawa M, Takenouchi N, Hara H, Matsuura E, Nozuma S, Takashima H, Izumo S, Watanabe T, Uchimaru K, Iwanaga M, Utsunomiya A, Tabara Y, Paul R, Yamano Y, Matsuoka M and Matsuda F.

HTLV-1 associated myelopathy/tropical spastic paraparesis in the Japanese population – a genome-wide association study.

 Proc Natl Acad Sci USA 118(11):e2004199118. doi: 10.1073/pnas.2004199118.

https://pubmed.ncbi.nlm.nih.gov/33649182/

Ohmachi K, Kinoshita T, Tobinai K, Ogawa G, Mizutani T, Yamauchi N, Fukuhara N, Uchida T, Yamamoto K, Miyazaki K, Tsukamoto N, Iida S, Utsumi T, Yoshida I, Imaizumi Y, Tokunaga T, Yoshida S, Masaki Y, Murayama T, Yakushijin Y, Suehiyo Y, Nosaka K, Dobashi N, Kuroda J, Takamatsu Y, Maruyama D, Ando K, Ishizawa K, Ogura M, Yoshino T, Hotta T, Tsukasaki K, Nagai H Japan Clinical Oncology Group.

A randomized phase 2/3 study of R-CHOP vs CHOP combined with dose-dense rituximab for DLBCL: the JCOG0601 trial.

Blood Adv 5(4):984-993,2021. doi: 10.1182/bloodadvances.2020002567.

https://pubmed.ncbi.nlm.nih.gov/33591324/