KUMAMOTO University

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研究実績RESEARCH ACHIEVEMENTS

  1. Sato E, Iriyama N, Tokuhira M, Takaku T, Ishikawa M, Nakazato T, Sugimoto KJ, Fujita H, Fujioka I, Asou N, Komatsu N, Kizaki M, Hatta Y, Kawaguchi T.

    Introduction of second-generation tyrosine kinase inhibitors may reduce the prognostic impact of high-risk patients, according to the European treatment and outcome study (EUTOS) score.

    Leuk Lymphoma. 2018 May;59(5):1105-1112. doi: 10.1080/10428194.2017.1365858. Epub 2017 Aug 25. PMID: 28838287.

    https://pubmed.ncbi.nlm.nih.gov/28838287/

  2. Ogura M, Yamamoto K, Morishima Y, Wakabayashi M, Tobinai K, Ando K, Uike N, Kurosawa M, Gomyo H, Taniwaki M, Nosaka K, Tsukamoto N, Shimoyama T, Fukuhara N, Yakushijin Y, Ohnishi K, Miyazaki K, Sawada K, Takayama N, Hanamura I, Nagai H, Kobayashi H, Usuki K, Kobayashi N, Ohyashiki K, Utsumi T, Kumagai K, Maruyama D, Ohmachi K, Matsuno Y, Nakamura S, Hotta T, Tsukasaki K; Japan Clinical Oncology Group- Lymphoma Study Group (JCOG-LSG).

    R-High-CHOP/CHASER/LEED with autologous stem cell transplantation in newly diagnosed mantle cell lymphoma: JCOG0406 STUDY.

    Cancer Sci. 2018 Sep;109(9):2830-2840. doi: 10.1111/cas.13719. Epub 2018 Jul 28. PMID: 29957865; PMCID: PMC6125440.

    https://pubmed.ncbi.nlm.nih.gov/29957865/

     

  3. Kawaguchi T.

    [Management of paroxysmal nocturnal hemoglobinuria: an update].

    Rinsho Ketsueki. 2018;59(6):703-710. Japanese. doi: 10.11406/rinketsu.59.703. PMID: 29973448.

    https://pubmed.ncbi.nlm.nih.gov/29973448/

     

  4. Ishikawa J, Matsumura I, Kawaguchi T, Kuroda J, Nakamae H, Miyamoto T, Matsuoka KI, Shibayama H, Hino M, Hirase C, Kamimura T, Shimose T, Akashi K, Kanakura Y.

    Efficacy and safety of switching to nilotinib in patients with CML-CP in major molecular response to imatinib: results of a multicenter phase II trial (NILSw trial).

    Int J Hematol. 2018 May;107(5):535-540. doi: 10.1007/s12185-018-2401-y. Epub 2018 Jan 23. PMID: 29362980.

  5. Iriyama N, Sugimoto KJ, Sato E, Takaku T, Tokuhira M, Nakazato T, Ishikawa M, Fujita H, Fujioka I, Kimura Y, Asou N, Kizaki M, Komatsu N, Hatta Y, Kawaguchi T.

    Comparison of the clinical outcomes of nilotinib and dasatinib therapies in newly diagnosed patients in the chronic phase of chronic myeloid leukemia: a retrospective analysis.

    Med Oncol. 2018 Sep 7;35(11):142. doi: 10.1007/s12032-018-1203-7. PMID: 30194496.

    https://pubmed.ncbi.nlm.nih.gov/30194496/

     

  6. Yasunaga JI, Matsuoka M.

    Oncogenic spiral by infectious pathogens: Cooperation of multiple factors in cancer development.

    Cancer Sci. 2018 Jan;109(1):24-32. doi: 10.1111/cas.13443. Epub 2017 Dec 3. PMID: 29143406; PMCID: PMC5765297.

    https://pubmed.ncbi.nlm.nih.gov/29143406/

     

  7. Fuji S, Utsunomiya A, Inoue Y, Miyagi T, Owatari S, Sawayama Y, Moriuchi Y, Choi I, Shindo T, Yoshida SI, Yamasaki S, Yamaguchi T, Fukuda T.

    Outcomes of patients with relapsed aggressive adult T-cell leukemia-lymphoma: clinical effectiveness of anti-CCR4 antibody and allogeneic hematopoietic stem cell transplantation.

    Haematologica. 2018 May;103(5):e211-e214. doi: 10.3324/haematol.2017.184564. Epub 2018 Jan 25. PMID: 29371324; PMCID: PMC5927966.

    https://pubmed.ncbi.nlm.nih.gov/29371324/

  8. Kuramitsu M, Okuma K, Nakashima M, Sato T, Sasaki D, Hasegawa H, Umeki K, Kubota R, Sasada K, Sobata R, Matsumoto C, Kaneko N, Tezuka K, Matsuoka S, Utsunomiya A, Koh KR, Ogata M, Ishitsuka K, Taki M, Nosaka K, Uchimaru K, Iwanaga M, Sagara Y, Yamano Y, Okayama A, Miura K, Satake M, Saito S, Watanabe T, Hamaguchi I.

    Development of reference material with assigned value for human T-cell leukemia virus type 1 quantitative PCR in Japan.

    Microbiol Immunol. 2018 Oct;62(10):673-676. doi: 10.1111/1348-0421.12644. PMID: 30125970.

    https://pubmed.ncbi.nlm.nih.gov/30125970/

     

  9. Yasunaga JI, Matsuoka M.

    Oncogenic spiral by infectious pathogens: Cooperation of multiple factors in cancer development.

    Cancer Sci. 2018 Jan;109(1):24-32. doi: 10.1111/cas.13443. Epub 2017 Dec 3. PMID: 29143406; PMCID: PMC5765297.

    https://pubmed.ncbi.nlm.nih.gov/29143406/

     

  10. Shichijo T, Fuji S, Tajima K, Kubo H, Nozaki K, Honda T, Yamaguchi J, Kawashima I, Kawajiri A, Takemura T, Onishi A, Ito A, Tanaka T, Inamoto Y, Kurosawa S, Kim SW, Fukuda T.

    Beneficial impact of low-dose rabbit anti-thymocyte globulin in unrelated hematopoietic stem cell transplantation: focusing on difference between stem cell sources.

    Bone Marrow Transplant. 2018 May;53(5):634-639. doi: 10.1038/s41409-017-0045-9. Epub 2018 Jan 15. PMID: 29335624.

    https://pubmed.ncbi.nlm.nih.gov/29335624/

  11. Oda S, Kawano Y, Okuno Y, Utsunomiya D, Nakaura T, Tsujita K, Yamashita Y.

    Base-to-apex gradient pattern of cardiac impairment identified on myocardial T1 mapping in cardiac amyloidosis.

    Radiol Case Rep. 2018 Oct 18;14(1):72-74. doi: 10.1016/j.radcr.2018.09.025. PMID: 30364800; PMCID: PMC6198104.

    https://pubmed.ncbi.nlm.nih.gov/30364800/

  12. Komohara Y, Noyori O, Saito Y, Takeya H, Baghdadi M, Kitagawa F, Hama N, Ishikawa K, Okuno Y, Nosaka K, Seino KI, Matsuoka M, Suzu S.

    Potential anti-lymphoma effect of M-CSFR inhibitor in adult T-cell leukemia/lymphoma.

    J Clin Exp Hematop. 2018;58(4):152-160. doi: 10.3960/jslrt.18034. PMID: 30541986; PMCID: PMC6407477.

    https://pubmed.ncbi.nlm.nih.gov/30541986/

     

  13. Fujii E, Inada Y, Kakoki M, Nishimura N, Endo S, Fujiwara S, Wada N, Kawano Y, Okuno Y, Sugimoto T, Hata H.

    Bufalin induces DNA damage response under hypoxic condition in myeloma cells.

    Oncol Lett. 2018 May;15(5):6443-6449. doi: 10.3892/ol.2018.8091. Epub 2018 Feb 21. PMID: 29616114; PMCID: PMC5876453.

    https://pubmed.ncbi.nlm.nih.gov/29440174/

  14. Hashi K, Imai C, Yahara K, Tahmina K, Hayashi T, Azuma T, Miyabe-Nishiwaki T, Sato H, Matsuoka M, Niimi S, Okamoto M, Hatakeyama M.

    Evaluating the origin and virulence of a Helicobacter pylori cagA-positive strain isolated from a non-human primate.

    Sci Rep. 2018 Oct 29;8(1):15981. doi: 10.1038/s41598-018-34425-4. PMID: 30374120; PMCID: PMC6206097.

    https://pubmed.ncbi.nlm.nih.gov/30374120/

  15. Shichijo T, Fuji S.

    Hematopoietic stem cell transplantation for T-cell lymphoma.

    Adv Cell Gene Ther. 2018;1:e6. doi.org/10.1002/acg2.6.

  16. Takagi S, Tsukamoto S, Park J, Johnson KE, Kawano Y, Moschetta M, Liu CJ, Mishima Y, Kokubun K, Manier S, Salem KZ, Huynh D, Sacco A, Forward J, Roccaro AM, Battinelli EM, Ghobrial IM.

    Platelets Enhance Multiple Myeloma Progression via IL-1β Upregulation.

    Clin Cancer Res. 2018 May 15;24(10):2430-2439. doi: 10.1158/1078-0432.CCR-17-2003. Epub 2018 Feb 9. PMID: 29440174.

    https://pubmed.ncbi.nlm.nih.gov/29440174/

     

  17. Fujioka I, Takaku T, Iriyama N, Tokuhira M, Kimura Y, Sato E, Ishikawa M, Nakazato T, Sugimoto KJ, Fujita H, Asou N, Kizaki M, Hatta Y, Komatsu N, Kawaguchi T.

    Features of vascular adverse events in Japanese patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors: a retrospective study of the CML Cooperative Study Group database.

    Ann Hematol. 2018 Nov;97(11):2081-2088. doi: 10.1007/s00277-018-3412-8. Epub 2018 Jun 26. PMID: 29946911.

    https://pubmed.ncbi.nlm.nih.gov/29946911/

  18. Satoru Kohgo, Shuhei Imoto, Ryoh Tokuda, Yuki Takamatsu, Nobuyo Higashi-Kuwata, Manabu Aoki, Masayuki Amano, Hisao Kansui, Kengo Onitsuka, Kenji Maeda, Hiroaki Mitsuya.

    Synthesis of 4’‐Substituted Purine 2’‐Deoxynucleosides and Their Activity against Human Immunodeficiency Virus Type 1 and Hepatitis B Virus.

    ChemistrySelect. 2018;3(11):3313–3317. doi.org/10.1002/slct.201800527

    https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/slct.201800527

     

  19. Ghosh AK, R Nyalapatla P, Kovela S, Rao KV, Brindisi M, Osswald HL, Amano M, Aoki M, Agniswamy J, Wang YF, Weber IT, Mitsuya H.

    Design and Synthesis of Highly Potent HIV-1 Protease Inhibitors Containing Tricyclic Fused Ring Systems as Novel P2 Ligands: Structure-Activity Studies, Biological and X-ray Structural Analysis.

    J Med Chem. 2018 May 24;61(10):4561-4577. doi: 10.1021/acs.jmedchem.8b00298. Epub 2018 May 15. PMID: 29763303; PMCID: PMC6044451.

    https://pubmed.ncbi.nlm.nih.gov/29763303/

  20. Naito T, Yasunaga JI, Mitobe Y, Shirai K, Sejima H, Ushirogawa H, Tanaka Y, Nakamura T, Hanada K, Fujii M, Matsuoka M, Saito M.

    Distinct gene expression signatures induced by viral transactivators of different HTLV-1 subgroups that confer a different risk of HAM/TSP.

    Retrovirology. 2018 Nov 6;15(1):72. doi: 10.1186/s12977-018-0454-x. PMID: 30400920; PMCID: PMC6219256.

    https://pubmed.ncbi.nlm.nih.gov/30400920/

  21. Kataoka K, Iwanaga M, Yasunaga JI, Nagata Y, Kitanaka A, Kameda T, Yoshimitsu M, Shiraishi Y, Sato-Otsubo A, Sanada M, Chiba K, Tanaka H, Ochi Y, Aoki K, Suzuki H, Shiozawa Y, Yoshizato T, Sato Y, Yoshida K, Nosaka K, Hishizawa M, Itonaga H, Imaizumi Y, Munakata W, Shide K, Kubuki Y, Hidaka T, Nakamaki T, Ishiyama K, Miyawaki S, Ishii R, Nureki O, Tobinai K, Miyazaki Y, Takaori-Kondo A, Shibata T, Miyano S, Ishitsuka K, Utsunomiya A, Shimoda K, Matsuoka M, Watanabe T, Ogawa S.

    Prognostic relevance of integrated genetic profiling in adult T-cell leukemia/lymphoma.

    Blood. 2018 Jan 11;131(2):215-225. doi: 10.1182/blood-2017-01-761874. Epub 2017 Oct 30. PMID: 29084771; PMCID: PMC5757690.

    https://pubmed.ncbi.nlm.nih.gov/29084771/

     

  22. Nakazato T, Iriyama N, Tokuhira M, Ishikawa M, Sato E, Takaku T, Sugimoto KJ, Fujita H, Fujioka I, Kimura Y, Aisa Y, Iwanaga E, Asou N, Kizaki M, Hatta Y, Komatsu N, Kawaguchi T.

    Incidence and outcome of second malignancies in patients with chronic myeloid leukemia during treatment with tyrosine kinase inhibitors.

    Med Oncol. 2018 May 30;35(7):99. doi: 10.1007/s12032-018-1159-7. PMID: 29846829.

  23. Naito T, Yasunaga JI, Mitobe Y, Shirai K, Sejima H, Ushirogawa H, Tanaka Y, Nakamura T, Hanada K, Fujii M, Matsuoka M, Saito M.

    Distinct gene expression signatures induced by viral transactivators of different HTLV-1 subgroups that confer a different risk of HAM/TSP.

    Retrovirology. 2018 Nov 6;15(1):72. doi: 10.1186/s12977-018-0454-x. PMID: 30400920; PMCID: PMC6219256.

    https://pubmed.ncbi.nlm.nih.gov/30400920/

  24. Shimazaki C, Hata H, Iida S, Ueda M, Katoh N, Sekijima Y, Ikeda S, Yazaki M, Fukushima W, Ando Y.

    Nationwide Survey of 741 Patients with Systemic Amyloid Light-chain Amyloidosis in Japan.

    Intern Med. 2018 Jan 15;57(2):181-187. doi: 10.2169/internalmedicine.9206-17. Epub 2017 Nov 1. PMID: 29093404; PMCID: PMC5820034.

    https://pubmed.ncbi.nlm.nih.gov/29093404/

     

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