KUMAMOTO University

R

研究実績RESEARCH ACHIEVEMENTS

  1. Nakazato T, Iriyama N, Tokuhira M, Ishikawa M, Sato E, Takaku T, Sugimoto KJ, Fujita H, Fujioka I, Kimura Y, Aisa Y, Iwanaga E, Asou N, Kizaki M, Hatta Y, Komatsu N, Kawaguchi T.

    Incidence and outcome of second malignancies in patients with chronic myeloid leukemia during treatment with tyrosine kinase inhibitors.

    Med Oncol. 2018 May 30;35(7):99. doi: 10.1007/s12032-018-1159-7. PMID: 29846829.

    https://pubmed.ncbi.nlm.nih.gov/29846829/

  2. Kumamoto H, Imoto S, Amano M, Kuwata-Higashi N, Baba M, Mitsuya H, Odanaka Y, Shimbara Matsubayashi S, Tanaka H, Haraguchi K.

    Synthesis, Anti-HBV, and Anti-HIV Activities of 3′-Halogenated Bis(hydroxymethyl)-cyclopentenyladenines.

    ACS Med Chem Lett. 2018 Nov 9;9(12):1211-1216. doi: 10.1021/acsmedchemlett.8b00374. PMID: 30613328; PMCID: PMC6295849.

    https://pubmed.ncbi.nlm.nih.gov/30613328/

  3. Kawashima I, Inamoto Y, Maeshima AM, Nomoto J, Tajima K, Honda T, Shichijo T, Kawajiri A, Takemura T, Onishi A, Ito A, Tanaka T, Fuji S, Kurosawa S, Kim SW, Maruyama D, Tobinai K, Kobayashi Y, Fukuda T.

    Double-Expressor Lymphoma Is Associated with Poor Outcomes after Allogeneic Hematopoietic Cell Transplantation.

    Biol Blood Marrow Transplant. 2018 Feb;24(2):294-300. doi: 10.1016/j.bbmt.2017.10.013. Epub 2017 Oct 14. PMID: 29037890.

    https://pubmed.ncbi.nlm.nih.gov/29037890/

     

  4. Ueda Y, Obara N, Yonemura Y, Noji H, Masuko M, Seki Y, Wada K, Matsuda T, Akiyama H, Ikezoe T, Chiba S, Kanda Y, Kawaguchi T, Shichishima T, Nakakuma H, Okamoto S, Nishimura JI, Kanakura Y, Ninomiya H.

    Effects of eculizumab treatment on quality of life in patients with paroxysmal nocturnal hemoglobinuria in Japan.

    Int J Hematol. 2018 Jun;107(6):656-665. doi: 10.1007/s12185-018-2409-3. Epub 2018 Jan 30. Erratum in: Int J Hematol. 2018 Aug;108(2):233-235. PMID: 29383624.

    https://pubmed.ncbi.nlm.nih.gov/29383624/

     

  5. Yasuma-Mitobe K, Matsuoka M.

    The Roles of Coinhibitory Receptors in Pathogenesis of Human Retroviral Infections.

    Front Immunol. 2018 Nov 27;9:2755. doi: 10.3389/fimmu.2018.02755. PMID: 30538707; PMCID: PMC6277675.

    https://pubmed.ncbi.nlm.nih.gov/30538707/

  6. Mahgoub M, Yasunaga JI, Iwami S, Nakaoka S, Koizumi Y, Shimura K, Matsuoka M.

    Sporadic on/off switching of HTLV-1 Tax expression is crucial to maintain the whole population of virus-induced leukemic cells.

    Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):E1269-E1278. doi: 10.1073/pnas.1715724115. Epub 2018 Jan 22. PMID: 29358408; PMCID: PMC5819419.

    https://pubmed.ncbi.nlm.nih.gov/29358408/

     

  7. Oda S, Nakaura T, Utsunomiya D, Hirakawa K, Takashio S, Izumiya Y, Tsujita K, Hata H, Ando Y, Yamashita Y.

    Late iodine enhancement and myocardial extracellular volume quantification in cardiac amyloidosis by using dual-energy cardiac computed tomography performed on a dual-layer spectral detector scanner.

    Amyloid. 2018 Jun;25(2):137-138. doi: 10.1080/13506129.2018.1424625. Epub 2018 Jan 8. PMID: 29308670.

    https://pubmed.ncbi.nlm.nih.gov/29308670/

  8. Song Z, Wu W, Chen M, Cheng W, Yu J, Fang J, Xu L, Yasunaga JI, Matsuoka M, Zhao T.

    Long Noncoding RNA ANRIL Supports Proliferation of Adult T-Cell Leukemia Cells through Cooperation with EZH2.

    J Virol. 2018 Nov 27;92(24):e00909-18. doi: 10.1128/JVI.00909-18. PMID: 30258009; PMCID: PMC6258931.

    https://pubmed.ncbi.nlm.nih.gov/30258009/

  9. Sato T, Coler-Reilly ALG, Yagishita N, Araya N, Inoue E, Furuta R, Watanabe T, Uchimaru K, Matsuoka M, Matsumoto N, Hasegawa Y, Yamano Y.

    Mogamulizumab (Anti-CCR4) in HTLV-1-Associated Myelopathy.

    N Engl J Med. 2018 Feb 8;378(6):529-538. doi: 10.1056/NEJMoa1704827. PMID: 29414279.

    https://pubmed.ncbi.nlm.nih.gov/29414279/

  10. Kawano Y, Zavidij O, Park J, Moschetta M, Kokubun K, Mouhieddine TH, Manier S, Mishima Y, Murakami N, Bustoros M, Pistofidis RS, Reidy M, Shen YJ, Rahmat M, Lukyanchykov P, Karreci ES, Tsukamoto S, Shi J, Takagi S, Huynh D, Sacco A, Tai YT, Chesi M, Bergsagel PL, Roccaro AM, Azzi J, Ghobrial IM.

    Blocking IFNAR1 inhibits multiple myeloma-driven Treg expansion and immunosuppression.

    J Clin Invest. 2018 Jun 1;128(6):2487-2499. doi: 10.1172/JCI88169. Epub 2018 May 14. PMID: 29558366; PMCID: PMC5983341.

    https://pubmed.ncbi.nlm.nih.gov/29558366/

  11. Hosokawa K, Sugimori C, Ishiyama K, Takamatsu H, Noji H, Shichishima T, Obara N, Chiba S, Ninomiya H, Shirasugi Y, Nakamura Y, Ando K, Ueda Y, Yonemura Y, Kawaguchi T, Nishimura JI, Kanakura Y, Nakao S.

    Establishment of a flow cytometry assay for detecting paroxysmal nocturnal hemoglobinuria-type cells specific to patients with bone marrow failure.

    Ann Hematol. 2018 Dec;97(12):2289-2297. doi: 10.1007/s00277-018-3443-1. Epub 2018 Jul 24. PMID: 30039297.

    https://pubmed.ncbi.nlm.nih.gov/30039297/

  12. Tokuhira M, Kimura Y, Sugimoto K, Nakazato T, Ishikawa M, Fujioka I, Takaku T, Iriyama N, Sato E, Fujita H, Hatta Y, Komatsu N, Asou N, Kizaki M, Kawaguchi T.

    Efficacy and safety of nilotinib therapy in patients with newly diagnosed chronic myeloid leukemia in the chronic phase.

    Med Oncol. 2018 Feb 13;35(3):38. doi: 10.1007/s12032-018-1093-8. PMID: 29442179.

    https://pubmed.ncbi.nlm.nih.gov/29442179/

  13. Fuji S, Kurosawa S, Inamoto Y, Murata T, Utsunomiya A, Uchimaru K, Yamasaki S, Inoue Y, Moriuchi Y, Choi I, Ogata M, Hidaka M, Yamaguchi T, Fukuda T.

    Role of up-front allogeneic hematopoietic stem cell transplantation for patients with aggressive adult T-cell leukemia-lymphoma: a decision analysis.

    Bone Marrow Transplant. 2018 Jul;53(7):905-908. doi: 10.1038/s41409-017-0082-4. Epub 2018 Jan 25. PMID: 29371687.

    https://pubmed.ncbi.nlm.nih.gov/29371687/

  14. Yuki A, Shinkuma S, Hayashi R, Fujikawa H, Kato T, Homma E, Hamade Y, Onodera O, Matsuoka M, Shimizu H, Iwata H, Abe R.

    CADM1 is a diagnostic marker in early-stage mycosis fungoides: Multicenter study of 58 cases.

    J Am Acad Dermatol. 2018 Dec;79(6):1039-1046. doi: 10.1016/j.jaad.2018.06.025. Epub 2018 Jun 19. PMID: 29928911.

    https://pubmed.ncbi.nlm.nih.gov/29928911/

     

  15. Tokunaga K, Yamamura A, Ueno S, Kikukawa Y, Yamaguchi S, Hidaka M, Matsuno N, Kawaguchi T, Matsuoka M, Okuno Y.

    Isolated Pancreatic Myeloid Sarcoma Associated with t(8;21)/RUNX1-RUNX1T1 Rearrangement.

    Intern Med. 2018 Feb 15;57(4):563-568. doi: 10.2169/internalmedicine.8912-17. Epub 2017 Nov 20. PMID: 29151502; PMCID: PMC5849554.

    https://pubmed.ncbi.nlm.nih.gov/29151502/

  16. Yamamura A, Kikukawa Y, Tokunaga K, Miyagawa E, Endo S, Miyake H, Hata H, Mitsuya H, Yoshida K, Matsuoka M.

    Pancytopenia and Myelodysplastic Changes in Aceruloplasminemia: A Case with a Novel Pathogenic Variant in the Ceruloplasmin Gene.

    Intern Med. 2018 Jul 1;57(13):1905-1910. doi: 10.2169/internalmedicine.9496-17. Epub 2018 Feb 9. PMID: 29434149; PMCID: PMC6064706.

    https://pubmed.ncbi.nlm.nih.gov/29434149/

  17. Kasamatsu T, Ozaki S, Saitoh T, Konishi J, Sunami K, Itagaki M, Asaoku H, Cho T, Handa H, Hagiwara S, Wakayama T, Negoro A, Takezako N, Harada N, Kuroda Y, Nakaseko C, Miyake T, Inoue N, Hata H, Shimazaki C, Ohno T, Kuroda J, Murayama T, Kobayashi T, Abe M, Ishida T, Nagura E, Shimizu K.

    Unsuppressed serum albumin levels may jeopardize the clinical relevance of the international staging system to patients with light chain myeloma.

    Hematol Oncol. 2018 Dec;36(5):792-800. doi: 10.1002/hon.2559. Epub 2018 Sep 19. PMID: 30176173.

    https://pubmed.ncbi.nlm.nih.gov/30176173/

  18. Tanaka A, Matsuoka M.

    HTLV-1 Alters T Cells for Viral Persistence and Transmission.

    Front Microbiol. 2018 Mar 20;9:461. doi: 10.3389/fmicb.2018.00461. PMID: 29615995; PMCID: PMC5869182.

    https://pubmed.ncbi.nlm.nih.gov/29615995/

  19. Tsukamoto S, Løvendorf MB, Park J, Salem KZ, Reagan MR, Manier S, Zavidij O, Rahmat M, Huynh D, Takagi S, Kawano Y, Kokubun K, Thrue CA, Nagano K, Petri A, Roccaro AM, Capelletti M, Baron R, Kauppinen S, Ghobrial IM.

    Inhibition of microRNA-138 enhances bone formation in multiple myeloma bone marrow niche.

    Leukemia. 2018 Aug;32(8):1739-1750. doi: 10.1038/s41375-018-0161-6. Epub 2018 Jun 20. PMID: 29925904.

    https://pubmed.ncbi.nlm.nih.gov/29925904/

  20. Saburi M, Ogata M, Itani K, Kohno K, Soga Y, Kondo Y, Kawano Y, Nakayama T.

    Rare concurrent indolent B-cell lymphoma and plasmablastic transformation of myeloma.

    J Clin Exp Hematop. 2018 Dec 13;58(4):175-179. doi: 10.3960/jslrt.18019. Epub 2018 Oct 10. PMID: 30305474; PMCID: PMC6407474.

    https://pubmed.ncbi.nlm.nih.gov/30305474/

  21. Oda S, Nakaura T, Utsunomiya D, Nakaura T, Takashio S, Izumiya Y, Tsujita K, Ueda M,Yamashita T, Ando Y, Kawano Y, Okuno Y, Hata H, Yamashita Y.

    Role of Noninvasive Diagnostic Imaging in Cardiac Amyloidosis

    A Review Cardiovascular Imaging Asia. 2018 Apr;2(2):97-106. doi.org/10.22468/cvia.2018.00059.

  22. Inoue Y, Fuji S, Tanosaki R, Inamoto Y, Tanaka T, Ito A, Okinaka K, Kurosawa S, Kim SW, Nakagama H, Fukuda T.

    Prognostic importance of pretransplant disease status for posttransplant outcomes in patients with adult T cell leukemia/lymphoma.

    Bone Marrow Transplant. 2018 Sep;53(9):1105-1115. doi: 10.1038/s41409-018-0139-z. Epub 2018 Mar 9. PMID: 29523883.

    https://pubmed.ncbi.nlm.nih.gov/29523883/

  23. Endo S, Nishimura N, Kawano Y, Ueno N, Ueno S, Tatetsu H, Komohara Y, Takeya M, Hata H, Mitsuya H, Masao M, Okuno Y.

    MUC1/KL-6 expression confers an aggressive phenotype upon myeloma cells.

    Biochem Biophys Res Commun. 2018 Dec 9;507(1-4):246-252. doi: 10.1016/j.bbrc.2018.11.016. Epub 2018 Nov 10. PMID: 30420285.

    https://pubmed.ncbi.nlm.nih.gov/30420285/

     

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