Higuchi Y, Tokunaga K, Watanabe Y, Kawakita T, Harada N, Yamaguchi S, Nosaka K, Mitsuya H, Asou N.

Lineage switch with t(6;11)(q27;q23) from T-cell lymphoblastic lymphoma to acute monoblastic leukemia at relapse.

Cancer Genet. 2016 Jun;209(6):267-71. doi: 10.1016/j.cancergen.2016.05.070. Epub 2016 May 18. PMID: 27268298.

https://pubmed.ncbi.nlm.nih.gov/27268298/

Kikukawa Y, Hata H, Ueda M, Yamashita T, Nasu S, Ide K, Ueno S, Ando Y, Mitsuya H, Okuno Y.

Successful Treatment of Amyloid Light-chain Amyloidosis in a Charcot-Marie-Tooth Disease Patient with Lenalidomide, Cyclophosphamide, and Dexamethasone.

Intern Med. 2016;55(18):2707-12. doi: 10.2169/internalmedicine.55.5815. Epub 2016 Sep 15. PMID: 27629972.

https://pubmed.ncbi.nlm.nih.gov/27629972/

Fujiwara S, Mochinaga H, Nakata H, Ohshima K, Matsumoto M, Uchiba M, Mikami Y, Hata H, Okuno Y, Mitsuya H, Nosaka K.

Successful treatment of TAFRO syndrome, a variant type of multicentric Castleman disease with thrombotic microangiopathy, with anti-IL-6 receptor antibody and steroids.

Int J Hematol. 2016 Jun;103(6):718-23. doi: 10.1007/s12185-016-1978-2. Epub 2016 Mar 15. PMID: 26980221.

https://pubmed.ncbi.nlm.nih.gov/26980221/

Makita S, Fuji S, Takano K, Tanaka T, Inoue Y, Ito R, Ito A, Hayashi Y, Tajima K, Okinaka K, Kurosawa S, Kim SW, Yamashita T, Tanosaki R, Tobinai K, Fukuda T.

Clinical Outcomes after Allogeneic Stem Cell Transplantation for Adult Lymphoblastic Lymphoma.

J Clin Exp Hematop. 2016;56(1):28-33. doi: 10.3960/jslrt.56.28. PMID: 27334855; PMCID: PMC6144282.

https://pubmed.ncbi.nlm.nih.gov/27334855/

Sugata K, Yasunaga J, Miura M, Akari H, Utsunomiya A, Nosaka K, Watanabe Y, Suzushima H, Koh KR, Nakagawa M, Kohara M, Matsuoka M.

Enhancement of anti-STLV-1/HTLV-1 immune responses through multimodal effects of anti-CCR4 antibody.

Sci Rep. 2016 Jun 2;6:27150. doi: 10.1038/srep27150. PMID: 27250643; PMCID: PMC4890010.

https://pubmed.ncbi.nlm.nih.gov/27250643/

Moschetta M, Kawano Y, Podar K.

Targeting the Bone Marrow Microenvironment.

Cancer Treat Res. 2016;169:63-102. doi: 10.1007/978-3-319-40320-5_6. PMID: 27696259.

Manier S, Kawano Y, Bianchi G, Roccaro AM, Ghobrial IM.

Cell autonomous and microenvironmental regulation of tumor progression in precursor states of multiple myeloma.

Curr Opin Hematol. 2016 Jul;23(4):426-33. doi: 10.1097/MOH.0000000000000259. PMID: 27101529.

https://pubmed.ncbi.nlm.nih.gov/27101529/

Glavey SV, Manier S, Sacco A, Salem K, Kawano Y, Bouyssou J, Ghobrial IM, Roccaro AM.

Epigenetics in Multiple Myeloma.

Cancer Treat Res. 2016;169:35-49. doi: 10.1007/978-3-319-40320-5_4. PMID: 27696257.

Ghosh AK, Osswald HL, Glauninger K, Agniswamy J, Wang YF, Hayashi H, Aoki M, Weber IT, Mitsuya H.

Probing Lipophilic Adamantyl Group as the P1-Ligand for HIV-1 Protease Inhibitors: Design, Synthesis, Protein X-ray Structural Studies, and Biological Evaluation.

J Med Chem. 2016 Jul 28;59(14):6826-37. doi: 10.1021/acs.jmedchem.6b00639. Epub 2016 Jul 7. PMID: 27389367; PMCID: PMC5360270.

https://pubmed.ncbi.nlm.nih.gov/27389367/

Yasuma K, Yasunaga J, Takemoto K, Sugata K, Mitobe Y, Takenouchi N, Nakagawa M, Suzuki Y, Matsuoka M.

HTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT).

PLoS Pathog. 2016 Jan 6;12(1):e1005372. doi: 10.1371/journal.ppat.1005372. PMID: 26735971; PMCID: PMC4703212.

https://pubmed.ncbi.nlm.nih.gov/26735971/

Yasuma K, Matsuzaki T, Yamano Y, Takashima H, Matsuoka M, Saito M.

HTLV-1 subgroups associated with the risk of HAM/TSP are related to viral and host gene expression in peripheral blood mononuclear cells, independent of the transactivation functions of the viral factors.

J Neurovirol. 2016 Aug;22(4):416-30. doi: 10.1007/s13365-015-0407-2. Epub 2015 Dec 3. PMID: 26635027.

https://pubmed.ncbi.nlm.nih.gov/26635027/

Endo S, Amano M, Nishimura N, Ueno N, Ueno S, Yuki H, Fujiwara S, Wada N, Hirata S, Hata H, Mitsuya H, Okuno Y.

Immunomodulatory drugs act as inhibitors of DNA methyltransferases and induce PU.1 up-regulation in myeloma cells.

Biochem Biophys Res Commun. 2016 Jan 8;469(2):236-42. doi: 10.1016/j.bbrc.2015.11.116. Epub 2015 Nov 30. PMID: 26657848.

https://pubmed.ncbi.nlm.nih.gov/26657848/

Kuribayashi W, Takizawa K, Sugata K, Kuramitsu M, Momose H, Sasaki E, Hiradate Y, Furuhata K, Asada Y, Iwama A, Matsuoka M, Mizukami T, Hamaguchi I.

Impact of the SCF signaling pathway on leukemia stem cell-mediated ATL initiation and progression in an HBZ transgenic mouse model.

Oncotarget. 2016 Aug 9;7(32):51027-51043. doi: 10.18632/oncotarget.10210. PMID: 27340921; PMCID: PMC5239456.

https://pubmed.ncbi.nlm.nih.gov/27340921/

Fuji S, Fujiwara H, Nakano N, Wake A, Inoue Y, Fukuda T, Hidaka M, Moriuchi Y, Miyamoto T, Uike N, Taguchi J, Eto T, Tomoyose T, Kondo T, Yamanoha A, Ichinohe T, Atsuta Y, Utsunomiya A; ATL Working Group of the Japan Society for Hematopoietic Cell Transplantation.

Early application of related SCT might improve clinical outcome in adult T-cell leukemia/lymphoma.

Bone Marrow Transplant. 2016 Feb;51(2):205-11. doi: 10.1038/bmt.2015.265. Epub 2015 Nov 2. PMID: 26524263.

https://pubmed.ncbi.nlm.nih.gov/26524263/

Salie ZL, Kirby KA, Michailidis E, Marchand B, Singh K, Rohan LC, Kodama EN, Mitsuya H, Parniak MA, Sarafianos SG.

Structural basis of HIV inhibition by translocation-defective RT inhibitor 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA).

Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):9274-9. doi: 10.1073/pnas.1605223113. Epub 2016 Aug 3. PMID: 27489345; PMCID: PMC4995989.

https://pubmed.ncbi.nlm.nih.gov/27489345/

Doi M, Murai I, Kunisue S, Setsu G, Uchio N, Tanaka R, Kobayashi S, Shimatani H, Hayashi H, Chao HW, Nakagawa Y, Takahashi Y, Hotta Y, Yasunaga J, Matsuoka M, Hastings MH, Kiyonari H, Okamura H.

Gpr176 is a Gz-linked orphan G-protein-coupled receptor that sets the pace of circadian behaviour.

Nat Commun. 2016 Feb 17;7:10583. doi: 10.1038/ncomms10583. PMID: 26882873; PMCID: PMC4757782.

https://pubmed.ncbi.nlm.nih.gov/26882873/

Kawatsuki A, Yasunaga JI, Mitobe Y, Green PL, Matsuoka M.

HTLV-1 bZIP factor protein targets the Rb/E2F-1 pathway to promote proliferation and apoptosis of primary CD4(+) T cells.

Oncogene. 2016 Aug 25;35(34):4509-17. doi: 10.1038/onc.2015.510. Epub 2016 Jan 25. PMID: 26804169; PMCID: PMC4959989.

https://pubmed.ncbi.nlm.nih.gov/26804169/

Haji S, Kiyasu J, Choi I, Suehiro Y, Toyoda K, Tsuda M, Takamatsu A, Nakashima Y, Miyoshi H, Shiratsuchi M, Yamasaki S, Uike N, Abe Y.

Administration of an anti-CC chemokine receptor 4 monoclonal antibody, mogamulizumab, before allogeneic bone marrow transplantation for adult T-cell leukemia/lymphoma.

Bone Marrow Transplant. 2016 Mar;51(3):432-4. doi: 10.1038/bmt.2015.254. Epub 2015 Nov 2. PMID: 26524267.

https://pubmed.ncbi.nlm.nih.gov/26524267/

Maeshima AM, Taniguchi H, Toyoda K, Yamauchi N, Makita S, Fukuhara S, Munakata W, Maruyama D, Kobayashi Y, Tobinai K.

Clinicopathological features of histological transformation from extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue to diffuse large B-cell lymphoma: an analysis of 467 patients.

Br J Haematol. 2016 Sep;174(6):923-31. doi: 10.1111/bjh.14153. Epub 2016 Jul 27. PMID: 27460179.

Kumamoto H, Fukano M, Nakano T, Iwagami K, Takeyama C, Kohgo S, Imoto S, Amano M, Kuwata-Higashi N, Aoki M, Abe H, Mitsuya H, Fukuhara K, Haraguchi K.

Diastereoselective Synthesis of 6″-(Z)- and 6″-(E)-Fluoro Analogues of Anti-hepatitis B Virus Agent Entecavir and Its Evaluation of the Activity and Toxicity Profile of the Diastereomers.

J Org Chem. 2016 Apr 1;81(7):2827-36. doi: 10.1021/acs.joc.6b00105. Epub 2016 Mar 24. PMID: 27009432.

https://pubmed.ncbi.nlm.nih.gov/27009432/

Sugata K, Yasunaga J, Kinosada H, Mitobe Y, Furuta R, Mahgoub M, Onishi C, Nakashima K, Ohshima K, Matsuoka M.

HTLV-1 Viral Factor HBZ Induces CCR4 to Promote T-cell Migration and Proliferation.

Cancer Res. 2016 Sep 1;76(17):5068-79. doi: 10.1158/0008-5472.CAN-16-0361. Epub 2016 Jul 11. PMID: 27402079.

https://pubmed.ncbi.nlm.nih.gov/27670680/

Kuriyama K, Fuji S, Inamoto Y, Tajima K, Tanaka T, Inoue Y, Ito R, Hayashi Y, Ito A, Kurosawa S, Kim SW, Yamashita T, Fukuda T.

Impact of low-dose rabbit anti-thymocyte globulin in unrelated hematopoietic stem cell transplantation.

Int J Hematol. 2016 Apr;103(4):453-60. doi: 10.1007/s12185-016-1947-9. Epub 2016 Feb 9. PMID: 26857285.

https://pubmed.ncbi.nlm.nih.gov/26857285/

Alam M, Kuwata T, Shimura K, Yokoyama M, Ramirez Valdez KP, Tanaka K, Maruta Y, Oishi S, Fujii N, Sato H, Matsuoka M, Matsushita S.

Enhanced antibody-mediated neutralization of HIV-1 variants that are resistant to fusion inhibitors.

Retrovirology. 2016 Sep 27;13(1):70. doi: 10.1186/s12977-016-0304-7. PMID: 27670680; PMCID: PMC5037607.

https://pubmed.ncbi.nlm.nih.gov/27670680/

Tanaka Y, Kurosawa S, Tajima K, Tanaka T, Ito R, Inoue Y, Okinaka K, Inamoto Y, Fuji S, Kim SW, Tanosaki R, Yamashita T, Fukuda T.

Analysis of non-relapse mortality and causes of death over 15 years following allogeneic hematopoietic stem cell transplantation.

Bone Marrow Transplant. 2016 Apr;51(4):553-9. doi: 10.1038/bmt.2015.330. Epub 2016 Jan 11. PMID: 26752142.

https://pubmed.ncbi.nlm.nih.gov/26752142/