Kogure Y, Kameda T, Koya J, Yoshimitsu M, Nosaka K, Yasunaga JI, Imaizumi Y, Watanabe M, Saito Y, Ito Y, McClure MB, Tabata M, Shingaki S, Yoshifuji K, Chiba K, Okada A, Kakiuchi N, Nannya Y, Kamiunten A, Tahira Y, Akizuki K, Sekine M, Shide K, Hidaka T, Kubuki Y, Kitanaka A, Hidaka M, Nakano N, Utsunomiya A, Sica RA, Acuna-Villaorduna A, Janakiram M, Shah UA, Ramos JC, Shibata T, Takeuchi K, Takaori-Kondo A, Miyazaki Y, Matsuoka M, Ishitsuka K, Shiraishi Y, Miyano S, Ogawa S, Ye BH, Shimoda K, Kataoka K.

Whole-genome landscape of adult T-cell leukemia/lymphoma.

Blood 139(7):967-982,2022. doi: 10.1182/blood.2021013568.

https://pubmed.ncbi.nlm.nih.gov/34695199/

Nosaka K, Kusumoto S, Nakano N, Choi I, Yoshimitsu M, Imaizumi Y, Hidaka M, Sasaki H, Makiyama J, Ohtsuka E, Jo T, Ogata M, Ito A, Yonekura K, Tatetsu H, Kato T, Kawakita T, Suehiro Y, Ishitsuka K, Iida S, Matsutani T, Utsunomiya A, Ueda R, Ishida T.

Clinical significance of the immunoglobulin G heavy-chain repertoire in peripheral blood mononuclear cells of adult T-cell leukemia-lymphoma patients receiving mogamulizumab.

Br J Haematol 196(3):629-638,2022. doi: 10.1111/bjh.17895. Epub 2021 Oct 10.

https://pubmed.ncbi.nlm.nih.gov/34632569/

Kunitomo K, Hirano T, Tsuji T.

Numerous Schistocytes in thrombotic thrombocytopenic purpura.

https://pubmed.ncbi.nlm.nih.gov/33095337/

Katsuya H, Cook LBM, Rowan AG, Melamed A, Turpin J, Ito J, Islam S, Miyazato P, Jek Yang Tan B, Matsuo M, Miyakawa T, Nakata H, Matsushita S, Taylor GP, Bangham CRM, Kimura S, Satou Y.

Clonality of HIV-1- and HTLV-1-Infected Cells in Naturally Coinfected Individuals.

Higuchi Y, Yasunaga JI, Matsuoka M.

HTLV-1’s foxy strategy for survival and Transmission.

Front Virol doi: 10.3389/fviro.2021.792659,2022.

https://www.frontiersin.org/articles/10.3389/fviro.2021.792659/full

Masayuki Amano, Ravikiran S Yedidi, Pedro Miguel Salcedo-Gómez, Hironori Hayashi, Kazuya Hasegawa, Cuthbert D Martyr, Arun K Ghosh, Hiroaki Mitsuya.

Fluorine-Modifications Contribute to Potent Antiviral Activity against Highly Drug-Resistant HIV-1 and Favorable Blood-Brain Barrier (BBB) Penetration Property of Novel Central Nervous System (CNS)-targeting HIV-1 Protease Inhibitors In Vitro.

Antimicrob Agents Chemother. 2022 Jan 3; AAC0171521. doi: 10.1128/AAC.01715-21.

https://journals.asm.org/doi/10.1128/AAC.01715-21

https://pubmed.ncbi.nlm.nih.gov/34978889/

Kawano Y, Sasano T, Arima Y, Kushima S, Tsujita K, Matsuoka M, Hata H.

A novel PDK1 inhibitor, JX06, inhibits glycolysis and induces apoptosis in multiple myeloma cells.

Biochem Biophys Res Commun 587: 153-159,2022. doi: 10.1016/j.bbrc.2021.11.102.

https://pubmed.ncbi.nlm.nih.gov/34875534/

Inoue Y, Nakano N, Fuji S, Eto T, Kawakita T, Suehiro Y, Miyamoto T, Sawayama Y, Uchida N, Kondo T, Kanda J, Atsuta Y, Fukuda T, Yoshimitsu M, Kato K, ATL Working Group of the Japan Society for Hematopoietic Cell Transplantation.

Impact of conditioning intensity and regimen on transplant outcomes in patients with adult T-cell leukemia-lymphoma.

Bone Marrow Transplant 56(12):2964-2974,2021.  doi: 10.1038/s41409-021-01445-0.

https://pubmed.ncbi.nlm.nih.gov/34462567/

Hiyoshi M, Takahashi N, Eltalkhawy YM, Noyori O, Lotfi S, Panaampon J, Okada S, Tanaka Y, Ueno T, Fujisawa JI, Sato Y, Suzuki T, Hasegawa H, Tokunaga M, Satou Y, Yasunaga JI, Matsuoka M, Utsunomiya A, Suzu S.

M-Sec induced by HTLV-1 mediates an efficient viral transmission.

PLoS Pathog 17(11):e1010126,2021.  doi: 10.1371/journal.ppat.1010126.

https://pubmed.ncbi.nlm.nih.gov/34843591/

Tanaka T, Nakamae H, Ito A, Fuji S, Hirose A, Eto T, Henzan H, Takase K, Yamasaki S, Makiyama J, Moriuchi Y, Choi I, Nakano N, Hiramoto N, Kato K, Sato T, Sawayama Y, Kim SW, Inoue Y, Inamoto Y, Fukuda T.

A Phase I/II Multicenter Trial of HLA-Haploidentical PBSCT with PTCy for Aggressive Adult T Cell Leukemia/Lymphoma.

Transplant Cell Ther 27(11):928 e1-e7,2021.doi: 10.1016/j.jtct.2021.07.010

https://pubmed.ncbi.nlm.nih.gov/34274491/

Kenji Maeda, Masayuki Amano, Yukari Uemura, Kiyoto Tsuchiya, Tomoko Matsushima, Kenta Noda, Yosuke Shimizu, Asuka Fujiwara, Yuki Takamatsu, Yasuko Ichikawa, Hidehiro Nishimura, Mari Kinoshita, Shota Matsumoto, Hiroyuki Gatanaga, Kazuhisa Yoshimura, Shin-Ichi Oka, Ayako Mikami, Wataru Sugiura, Toshiyuki Sato, Tomokazu Yoshida, Shinya Shimada, Hiroaki Mitsuya.

Correlates of neutralizing/SARS-CoV-2-S1-binding antibody response with adverse effects and immune kinetics in BNT162b2-vaccinated individuals.

Sci Rep. 2021 Nov 24;11(1):22848. doi: 10.1038/s41598-021-01930-y.

https://pubmed.ncbi.nlm.nih.gov/34819514/

Fujimoto Y, Ueno S, Oda K, Gunda N, Shimomura Y, Nishimura Y, Yamaguchi A, Kuwano A, Ito Y, Baba Y, Nishigaki A, Michiwaki N, Uchino S, Kurogi K, Kawano Y, Matsuoka M, Saito H, Okuno Y, Jono H.

Relationship between serum bortezomib concentration and emergence of diarrhea in patients with multiple myeloma and/or AL amyloidosis.

Cancers 13(22),5674,2021. doi: 10.3390/cancers13225674.

https://pubmed.ncbi.nlm.nih.gov/34830830/

Ito A, Nakano N, Tanaka T, Fuji S, Makiyama J, Inoue Y, Choi I, Nakamae H, Nagafuji K, Takase K, Machida S, Takahashi T, Sawayama Y, Kamimura T, Kato K, Kawakita T, Ogata M, Sakai R, Shiratori S, Uchimaru K, Inamoto Y, Utsunomiya A, Fukuda T.

Improved survival of patients with aggressive ATL by increased use of allo-HCT: a prospective observational study.

Blood Adv 5(20):4156-66,2021. doi: 10.1182/bloodadvances.2021004932.

https://pubmed.ncbi.nlm.nih.gov/34500464/

Abdallah MG, Niibori-Nambu A, Morii M, Yokomizo T, Yokomizo T, Ideue T, Kubota S, Teoh VSI, Mok MMH, Wang CQ, Omar AA, Tokunaga K, Iwanaga E, Matsuoka M, Asou N, Nakagata N, Araki K, AboElenin M, Madboly SH, Sashida G, Osato M.

RUNX1-ETO (RUNX1-RUNX1T1) induces myeloid leukemia in mice in an age-dependent manner.

Leukemia 35(10):2983-2988,2021. doi: 10.1038/s41375-021-01268-4

https://pubmed.ncbi.nlm.nih.gov/34148054/

Ito S, Iwanaga M, Nosaka K, Imaizumi Y, Ishitsuka K, Amano M, Utsunomiya A, Tokura Y, Watanabe T, Uchimaru K, Tsukasaki K, Collaborative Investigators.

Epidemiology of adult T-cell leukemia-lymphoma in Japan: An updated analysis, 2012-2013.

Cancer Sci 112(10):4346-4354,2021. doi: 10.1111/cas.15097.

https://pubmed.ncbi.nlm.nih.gov/34355480/

Inoue Y, Okinaka K, Fuji S, Inamoto Y, Uchida N, Toya T, Ikegame K, Eto T, Ozawa Y, Iwato K, Kanda Y, Atsuta Y, Ogata M, Fukuda T, Transplant Complications Working Group of The Japan Society for Hematopoietic Cell Transplantation.

Severe acute graft-versus-host disease increases the incidence of blood stream infection and mortality after allogeneic hematopoietic cell transplantation: Japanese transplant registry study.

Bone Marrow Transplant 56(9):2125-36,2021.  doi: 10.1038/s41409-021-01291-0.

https://pubmed.ncbi.nlm.nih.gov/33875815/

Izutsu K, Ando K, Nishikori M, Shibayama H, Teshima T, Kuroda J, Kato K, Imaizumi Y, Nosaka K, Sakai R, Hojo S, Nakanishi T, Rai S.

Phase II study of tazemetostat for relapsed or refractory B-cell non-Hodgkin lymphoma with EZH2 mutation in Japan.

Cancer Sci 112(9):3627-3635,2021. doi: 10.1111/cas.15040.

https://pubmed.ncbi.nlm.nih.gov/34159682/

Ono A, Kitano Y, Imai K, Matsumoto T, Endo S, Tokunaga K, Hayashi H, Yamashita YI, Matsuoka M, Baba H.

A case of primary nonleukemic myeloid sarcoma of the spleen, successfully treated by surgery and hematopoietic stem cell transplantation.

Surg Case Rep 7(1):180,2021. doi: 10.1186/s40792-021-01257-w.

https://pubmed.ncbi.nlm.nih.gov/34379239/

Hosokawa K, Ishiyama K, Ikemoto T, Sugimori C, Noji H, Shichishima T, Obara N, Chiba S, Ninomiya H, Nguyen M.A.T, Shirasugi Y, Nakamura Y, Ando K, Ueda Y, Yonemura Y, Kawaguchi T, Nishimura J, Kanakura Y, Nakao S.

The clinical significance of PNH-phenotype cells accounting for < 0.01% of total granulocytes detected by the Clinical and Laboratory Standards Institute methods in patients with bone marrow failure.

Ann Hematol 100(8):1975-82,2021. doi: 10.1007/s00277-020-04314-w

https://pubmed.ncbi.nlm.nih.gov/33095337/

Toyoda K, Yasunaga JI, Choi I, Suehiro Y, Uike N, Okamura J, Matsuoka M.

The HTLV-1 proviral status is a potential prognostic biomarker for adult T-cell leukemia-lymphoma treated with allogeneic stem cell transplantation.

Bone Marrow Transplant 56(8):2027-2030,2021. doi: 10.1038/s41409-021-01311-z.

https://pubmed.ncbi.nlm.nih.gov/33927348/

Travis Chia, Tomofumi Nakamura, Masayuki Amano, Nobutoki Takamune, Masao Matsuoka, Hirotomo Nakata

A small molecule, ACAi-028, with anti-HIV-1 activity targets a novel hydrophobic pocket on HIV-1 capsid

Antimicrob Agents Chemother. 2021 Jul 6;AAC0103921. doi: 10.1128/AAC.01039-21. Online ahead of print.

https://pubmed.ncbi.nlm.nih.gov/34228546/

Kawakita T, Hirano T, Inoue Y, Irie Y, Sugitani H, Kubota A, Watanabe M, Ueno M, Mitsui N, Yamaguchi S, Inoue Y, Sakai T, Harada N, Matsuoka M, Hidaka M.

Feasibility of an intensified myeloablative conditioning regimen consisting of busulfan, fludarabine, cytarabine, and total body irradiation before single cord blood transplantation in elderly patients.

Int J Hematol 114(1):85-93,2021. doi: 10.1007/s12185-021-03131-9.

https://pubmed.ncbi.nlm.nih.gov/33740219/

Ohguchi H, Park PM, Wang T, Gryder BE, Ogiya D, Kurata K, Zhang X, Li D, Pei C, Masuda T, Johansson C, Wimalasena VK, Kim Y, Hino S, Usuki S, Kawano Y, Samur MK, Tai YT, Munshi NC, Matsuoka M, Ohtsuki S, Nakao M, Minami T, Lauberth S, Khan J, Oppermann U, Durbin AD, Anderson KC, Hideshima T, Qi J.

Lysine Demethylase 5A is Required for MYC Driven Transcription in Multiple Myeloma.

Blood Cancer Discov 2(4):370-387,2021. doi: 10.1158/2643-3230.BCD-20-0108.

https://pubmed.ncbi.nlm.nih.gov/34258103/

Sakata K, Kikuchi J, Emoto K, Kotaki T, Ota Y, Nishina N, Hanaoka H, Otomo K, Suzuki K, Kaneko Y, Takeuchi T.

Refractory IgG4-related Pleural Disease with Chylothorax: A Case Report and Literature Review.

Intern Med 60(13):2135-2143,2021.doi: 10.2169/internalmedicine.6313-20. Epub 2021 Feb 1.

https://pubmed.ncbi.nlm.nih.gov/33518567/