KUMAMOTO University

R

研究業績RESEARCH ACHIEVEMENTS

  1. Fuji S, Inoue Y, Utsunomiya A, Moriuchi Y, Choi I, Otsuka E, Henzan H, Kato K, Nakachi S, Yamamoto H, Fukuda T.

    Impact of pretransplant central nervous system invasion in patients with aggressive adult T-cell leukemia lymphoma.

    Bone Marrow Transplant. 2019 Jan;54(1):134-137. doi: 10.1038/s41409-018-0248-8. Epub 2018 Jun 13. PMID: 29899570.

  2. Inoue Y, Fuji S, Tanosaki R, Inamoto Y, Tanaka T, Ito A, Okinaka K, Kurosawa S, Kim SW, Nakagama H, Fukuda T.

    Prognostic importance of pretransplant disease status for posttransplant outcomes in patients with adult T cell leukemia/lymphoma.

    Bone Marrow Transplant. 2018 Sep;53(9):1105-1115. doi: 10.1038/s41409-018-0139-z. Epub 2018 Mar 9. PMID: 29523883.

  3. Ishida T, Jo T, Takemoto S, Suzushima H, Suehiro Y, Choi I, Yoshimitsu M, Saburi Y, Nosaka K, Utsunomiya A, Kobayashi Y, Yamamoto K, Fujiwara H, Ishitsuka K, Yoshida S, Taira N, Imada K, Kato K, Moriuchi Y, Yoshimura K, Takahashi T, Tobinai K, Ueda R.

    Follow-up of a randomised phase II study of chemotherapy alone or in combination with mogamulizumab in newly diagnosed aggressive adult T-cell leukaemia-lymphoma: impact on allogeneic haematopoietic stem cell transplantation.

    Br J Haematol. 2019 Feb;184(3):479-483. doi: 10.1111/bjh.15123. Epub 2018 Feb 7. PMID: 29411857.

  4. Fuji S, Utsunomiya A, Inoue Y, Miyagi T, Owatari S, Sawayama Y, Moriuchi Y, Choi I, Shindo T, Yoshida SI, Yamasaki S, Yamaguchi T, Fukuda T.

    Outcomes of patients with relapsed aggressive adult T-cell leukemia-lymphoma: clinical effectiveness of anti-CCR4 antibody and allogeneic hematopoietic stem cell transplantation.

    Haematologica. 2018 May;103(5):e211-e214. doi: 10.3324/haematol.2017.184564. Epub 2018 Jan 25. PMID: 29371324; PMCID: PMC5927966.

  5. Fuji S, Kurosawa S, Inamoto Y, Murata T, Utsunomiya A, Uchimaru K, Yamasaki S, Inoue Y, Moriuchi Y, Choi I, Ogata M, Hidaka M, Yamaguchi T, Fukuda T.

    Role of up-front allogeneic hematopoietic stem cell transplantation for patients with aggressive adult T-cell leukemia-lymphoma: a decision analysis.

    Bone Marrow Transplant. 2018 Jul;53(7):905-908. doi: 10.1038/s41409-017-0082-4. Epub 2018 Jan 25. PMID: 29371687.

  6. Yasunaga JI, Matsuoka M.

    Oncogenic spiral by infectious pathogens: Cooperation of multiple factors in cancer development.

    Cancer Sci. 2018 Jan;109(1):24-32. doi: 10.1111/cas.13443. Epub 2017 Dec 3. PMID: 29143406; PMCID: PMC5765297.

  7. Tanaka A, Matsuoka M.

    HTLV-1 Alters T Cells for Viral Persistence and Transmission.

    Front Microbiol. 2018 Mar 20;9:461. doi: 10.3389/fmicb.2018.00461. PMID: 29615995; PMCID: PMC5869182.

  8. Inoue Y, Endo S, Matsuno N, Kikukawa Y, Shichijo T, Koga K, Takaki A, Iwanaga K, Nishimura N, Fuji S, Fukuda T, Nosaka K, Matsuoka M.

    Safety of mogamulizumab for relapsed ATL after allogeneic hematopoietic cell transplantation.

    Bone Marrow Transplant. 2019 Feb;54(2):338-342. doi: 10.1038/s41409-018-0291-5. Epub 2018 Aug 16. PMID: 30116017.

  9. Song Z, Wu W, Chen M, Cheng W, Yu J, Fang J, Xu L, Yasunaga JI, Matsuoka M, Zhao T.

    Long Noncoding RNA ANRIL Supports Proliferation of Adult T-Cell Leukemia Cells through Cooperation with EZH2.

    J Virol. 2018 Nov 27;92(24):e00909-18. doi: 10.1128/JVI.00909-18. PMID: 30258009; PMCID: PMC6258931.

  10. Naito T, Yasunaga JI, Mitobe Y, Shirai K, Sejima H, Ushirogawa H, Tanaka Y, Nakamura T, Hanada K, Fujii M, Matsuoka M, Saito M.

    Distinct gene expression signatures induced by viral transactivators of different HTLV-1 subgroups that confer a different risk of HAM/TSP.

    Retrovirology. 2018 Nov 6;15(1):72. doi: 10.1186/s12977-018-0454-x. PMID: 30400920; PMCID: PMC6219256.

  11. Yasuma-Mitobe K, Matsuoka M.

    The Roles of Coinhibitory Receptors in Pathogenesis of Human Retroviral Infections.

    Front Immunol. 2018 Nov 27;9:2755. doi: 10.3389/fimmu.2018.02755. PMID: 30538707; PMCID: PMC6277675.

  12. Kinosada H, Yasunaga JI, Shimura K, Miyazato P, Onishi C, Iyoda T, Inaba K, Matsuoka M.

    HTLV-1 bZIP Factor Enhances T-Cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory Receptors.

    PLoS Pathog. 2017 Jan 3;13(1):e1006120. doi: 10.1371/journal.ppat.1006120. Erratum in: PLoS Pathog. 2017 Feb 23;13(2):e1006228. PMID: 28046066; PMCID: PMC5234849.

  13. Nishimura N, Endo S, Ueno S, Ueno N, Tatetsu H, Hirata S, Hata H, Komohara Y, Takeya M, Mitsuya H, Okuno Y.

    A xenograft model reveals that PU.1 functions as a tumor suppressor for multiple myeloma in vivo.

    Biochem Biophys Res Commun. 2017 May 13;486(4):916-922. doi: 10.1016/j.bbrc.2017.03.124. Epub 2017 Mar 24. PMID: 28347818.

  14. Ueno N, Nishimura N, Ueno S, Endo S, Tatetsu H, Hirata S, Hata H, Matsuoka M, Mitsuya H, Okuno Y.

    PU.1 acts as tumor suppressor for myeloma cells through direct transcriptional repression of IRF4.

    Oncogene. 2017 Aug;36(31):4481-4497. doi: 10.1038/onc.2017.79. Epub 2017 Apr 3. PMID: 28368411.

  15. Makita S, Munakata W, Watabe D, Maeshima AM, Taniguchi H, Toyoda K, Yamauchi N, Fukuhara S, Maruyama D, Kobayashi Y, Tobinai K.

    Azacitidine-induced acute lung injury in a patient with therapy-related myelodysplastic syndrome.

    J Int Med Res. 2017 Apr;45(2):886-893. doi: 10.1177/0300060517698331. Epub 2017 Mar 16. PMID: 28415946; PMCID: PMC5536648.

  16. Fuji S, Yamaguchi T, Inoue Y, Utsunomiya A, Moriuchi Y, Uchimaru K, Owatari S, Miyagi T, Taguchi J, Choi I, Otsuka E, Nakachi S, Yamamoto H, Kurosawa S, Tobinai K, Fukuda T.

    Development of a modified prognostic index for patients with aggressive adult T-cell leukemia-lymphoma aged 70 years or younger: possible risk-adapted management strategies including allogeneic transplantation.

    Haematologica. 2017 Jul;102(7):1258-1265. doi: 10.3324/haematol.2017.164996. Epub 2017 Mar 24. PMID: 28341734; PMCID: PMC5566038.

  17. Kawano Y, Roccaro AM, Ghobrial IM, Azzi J.

    Multiple Myeloma and the Immune Microenvironment.

    Curr Cancer Drug Targets. 2017;17(9):806-818. doi: 10.2174/1568009617666170214102301. PMID: 28201978.

  18. Tanaka Y, Kurosawa S, Tajima K, Tanaka T, Ito R, Inoue Y, Okinaka K, Inamoto Y, Fuji S, Kim SW, Tanosaki R, Yamashita T, Fukuda T.

    Increased incidence of oral and gastrointestinal secondary cancer after allogeneic hematopoietic stem cell transplantation.

    Bone Marrow Transplant. 2017 May;52(5):789-791. doi: 10.1038/bmt.2017.4. Epub 2017 Feb 13. PMID: 28194030.

  19. Kawajiri A, Fuji S, Tanaka Y, Kono C, Hirakawa T, Tanaka T, Ito R, Inoue Y, Okinaka K, Kurosawa S, Inamoto Y, Kim SW, Yamashita T, Fukuda T.

    Clinical impact of hyperglycemia on days 0-7 after allogeneic stem cell transplantation.

    Bone Marrow Transplant. 2017 Aug;52(8):1156-1163. doi: 10.1038/bmt.2017.27. Epub 2017 Mar 20. PMID: 28319076.

  20. Ghosh AK, Brindisi M, Nyalapatla PR, Takayama J, Ella-Menye JR, Yashchuk S, Agniswamy J, Wang YF, Aoki M, Amano M, Weber IT, Mitsuya H.

    Design of novel HIV-1 protease inhibitors incorporating isophthalamide-derived P2-P3 ligands: Synthesis, biological evaluation and X-ray structural studies of inhibitor-HIV-1 protease complex.

    Bioorg Med Chem. 2017 Oct 1;25(19):5114-5127. doi: 10.1016/j.bmc.2017.04.005. Epub 2017 Apr 9. PMID: 28434781; PMCID: PMC5617771.

  21. Kumamoto H, Fukano M, Imoto S, Kohgo S, Odanaka Y, Amano M, Kuwata-Higashi N, Mitsuya H, Haraguchi K, Fukuhara K.

    A novel entecavir analogue constructing with a spiro[2.4]heptane core structure in the aglycon moiety: Its synthesis and evaluation for anti-hepatitis B virus activity.

    Nucleosides Nucleotides Nucleic Acids. 2017 Jul 3;36(7):463-473. doi: 10.1080/15257770.2017.1322209. Epub 2017 Jun 2. PMID: 28574799.

  22. Amano M, Miguel Salcedo-Gómez P, Yedidi RS, Delino NS, Nakata H, Venkateswara Rao K, Ghosh AK, Mitsuya H.

    GRL-09510, a Unique P2-Crown-Tetrahydrofuranylurethane -Containing HIV-1 Protease Inhibitor, Maintains Its Favorable Antiviral Activity against Highly-Drug-Resistant HIV-1 Variants in vitro.

    Sci Rep. 2017 Sep 25;7(1):12235. doi: 10.1038/s41598-017-12052-9. PMID: 28947797; PMCID: PMC5613016.

  23. Ghosh AK, Sean Fyvie W, Brindisi M, Steffey M, Agniswamy J, Wang YF, Aoki M, Amano M, Weber IT, Mitsuya H.

    Design, synthesis, X-ray studies, and biological evaluation of novel macrocyclic HIV-1 protease inhibitors involving the P1′-P2′ ligands.

    Bioorg Med Chem Lett. 2017 Nov 1;27(21):4925-4931. doi: 10.1016/j.bmcl.2017.09.003. Epub 2017 Sep 6. PMID: 28958624; PMCID: PMC5647257.

  24. Ghosh AK, Fyvie WS, Brindisi M, Steffey M, Agniswamy J, Wang YF, Aoki M, Amano M, Weber IT, Mitsuya H.

    Design, Synthesis, Biological Evaluation, and X-ray Studies of HIV-1 Protease Inhibitors with Modified P2′ Ligands of Darunavir.

    ChemMedChem. 2017 Dec 7;12(23):1942-1952. doi: 10.1002/cmdc.201700614. Epub 2017 Nov 24. PMID: 29110408; PMCID: PMC5896574.

CONTACT US

C

  • 患者様へ

    外来診療の方は外来予約センターより
    ご予約をお願いいたします。
    外来予約センター

  • 学生・研修医・医療関係者の方へ

    TEL
    096-373-5156
    FAX
    096-373-5158
    Mail
    nikyo@kumamoto-u.ac.jp
Copyright 2019 KUMAMOTO University HRI All Rights Reserved.