KUMAMOTO University

R

研究業績RESEARCH ACHIEVEMENTS

  1. 76.

    Tanaka Y, Kurosawa S, Tajima K, Tanaka T, Ito R, Inoue Y, Okinaka K, Inamoto Y, Fuji S, Kim SW, Tanosaki R, Yamashita T, Fukuda T.

    Increased incidence of oral and gastrointestinal secondary cancer after allogeneic hematopoietic stem cell transplantation.

    Bone Marrow Transplant. 2017 May;52(5):789-791. doi: 10.1038/bmt.2017.4. Epub 2017 Feb 13. PMID: 28194030.

  2. 77.

    Makita S, Munakata W, Watabe D, Maeshima AM, Taniguchi H, Toyoda K, Yamauchi N, Fukuhara S, Maruyama D, Kobayashi Y, Tobinai K.

    Azacitidine-induced acute lung injury in a patient with therapy-related myelodysplastic syndrome.

    J Int Med Res. 2017 Apr;45(2):886-893. doi: 10.1177/0300060517698331. Epub 2017 Mar 16. PMID: 28415946; PMCID: PMC5536648.

  3. 78.

    Kinosada H, Yasunaga JI, Shimura K, Miyazato P, Onishi C, Iyoda T, Inaba K, Matsuoka M.

    HTLV-1 bZIP Factor Enhances T-Cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory Receptors.

    PLoS Pathog. 2017 Jan 3;13(1):e1006120. doi: 10.1371/journal.ppat.1006120. Erratum in: PLoS Pathog. 2017 Feb 23;13(2):e1006228. PMID: 28046066; PMCID: PMC5234849.

  4. 79.

    Kawano Y, Roccaro AM, Ghobrial IM, Azzi J.

    Multiple Myeloma and the Immune Microenvironment.

    Curr Cancer Drug Targets. 2017;17(9):806-818. doi: 10.2174/1568009617666170214102301. PMID: 28201978.

  5. 80.

    Amano M, Salcedo-Gómez PM, Zhao R, Yedidi RS, Das D, Bulut H, Delino NS, Sheri VR, Ghosh AK, Mitsuya H.

    A Modified P1 Moiety Enhances In Vitro Antiviral Activity against Various Multidrug-Resistant HIV-1 Variants and In Vitro Central Nervous System Penetration Properties of a Novel Nonpeptidic Protease Inhibitor, GRL-10413.

    Antimicrob Agents Chemother. 2016 Nov 21;60(12):7046-7059. doi: 10.1128/AAC.01428-16. PMID: 27620483; PMCID: PMC5118983.

  6. 81.

    Fuji S, Inoue Y, Utsunomiya A, Moriuchi Y, Uchimaru K, Choi I, Otsuka E, Henzan H, Kato K, Tomoyose T, Yamamoto H, Kurosawa S, Matsuoka K, Yamaguchi T, Fukuda T.

    Pretransplantation Anti-CCR4 Antibody Mogamulizumab Against Adult T-Cell Leukemia/Lymphoma Is Associated With Significantly Increased Risks of Severe and Corticosteroid-Refractory Graft-Versus-Host Disease, Nonrelapse Mortality, and Overall Mortality.

    J Clin Oncol. 2016 Oct 1;34(28):3426-33. doi: 10.1200/JCO.2016.67.8250. Epub 2016 Aug 9. PMID: 27507878.

  7. 82.

    Nakamura T, Campbell JR, Moore AR, Otsu S, Aikawa H, Tamamura H, Mitsuya H.

    Development and validation of a cell-based assay system to assess human immunodeficiency virus type 1 integrase multimerization.

    J Virol Methods. 2016 Oct;236:196-206. doi: 10.1016/j.jviromet.2016.07.023. Epub 2016 Jul 26. PMID: 27474494.

  8. 83.

    Alam M, Kuwata T, Shimura K, Yokoyama M, Ramirez Valdez KP, Tanaka K, Maruta Y, Oishi S, Fujii N, Sato H, Matsuoka M, Matsushita S.

    Enhanced antibody-mediated neutralization of HIV-1 variants that are resistant to fusion inhibitors.

    Retrovirology. 2016 Sep 27;13(1):70. doi: 10.1186/s12977-016-0304-7. PMID: 27670680; PMCID: PMC5037607.

  9. 84.

    Sugata K, Yasunaga J, Kinosada H, Mitobe Y, Furuta R, Mahgoub M, Onishi C, Nakashima K, Ohshima K, Matsuoka M.

    HTLV-1 Viral Factor HBZ Induces CCR4 to Promote T-cell Migration and Proliferation.

    Cancer Res. 2016 Sep 1;76(17):5068-79. doi: 10.1158/0008-5472.CAN-16-0361. Epub 2016 Jul 11. PMID: 27402079.

  10. 85.

    Maeshima AM, Taniguchi H, Toyoda K, Yamauchi N, Makita S, Fukuhara S, Munakata W, Maruyama D, Kobayashi Y, Tobinai K.

    Clinicopathological features of histological transformation from extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue to diffuse large B-cell lymphoma: an analysis of 467 patients.

    Br J Haematol. 2016 Sep;174(6):923-31. doi: 10.1111/bjh.14153. Epub 2016 Jul 27. PMID: 27460179.

  11. 86.

    Kawatsuki A, Yasunaga JI, Mitobe Y, Green PL, Matsuoka M.

    HTLV-1 bZIP factor protein targets the Rb/E2F-1 pathway to promote proliferation and apoptosis of primary CD4(+) T cells.

    Oncogene. 2016 Aug 25;35(34):4509-17. doi: 10.1038/onc.2015.510. Epub 2016 Jan 25. PMID: 26804169; PMCID: PMC4959989.

  12. 87.

    Salie ZL, Kirby KA, Michailidis E, Marchand B, Singh K, Rohan LC, Kodama EN, Mitsuya H, Parniak MA, Sarafianos SG.

    Structural basis of HIV inhibition by translocation-defective RT inhibitor 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA).

    Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):9274-9. doi: 10.1073/pnas.1605223113. Epub 2016 Aug 3. PMID: 27489345; PMCID: PMC4995989.

  13. 88.

    Kuribayashi W, Takizawa K, Sugata K, Kuramitsu M, Momose H, Sasaki E, Hiradate Y, Furuhata K, Asada Y, Iwama A, Matsuoka M, Mizukami T, Hamaguchi I.

    Impact of the SCF signaling pathway on leukemia stem cell-mediated ATL initiation and progression in an HBZ transgenic mouse model.

    Oncotarget. 2016 Aug 9;7(32):51027-51043. doi: 10.18632/oncotarget.10210. PMID: 27340921; PMCID: PMC5239456.

  14. 89.

    Yasuma K, Matsuzaki T, Yamano Y, Takashima H, Matsuoka M, Saito M.

    HTLV-1 subgroups associated with the risk of HAM/TSP are related to viral and host gene expression in peripheral blood mononuclear cells, independent of the transactivation functions of the viral factors.

    J Neurovirol. 2016 Aug;22(4):416-30. doi: 10.1007/s13365-015-0407-2. Epub 2015 Dec 3. PMID: 26635027.

  15. 90.

    Ghosh AK, Osswald HL, Glauninger K, Agniswamy J, Wang YF, Hayashi H, Aoki M, Weber IT, Mitsuya H. Probing Lipophilic Adamantyl Group as the P1-Ligand for HIV-1 Protease Inhibitors: Design, Synthesis, Protein X-ray Structural Studies, and Biological Evaluation. J Med Chem. 2016 Jul 28;59(14):6826-37. doi: 10.1021/acs.jmedchem.6b00639. Epub 2016 Jul 7. PMID: 27389367; PMCID: PMC5360270.

  16. 91.

    Manier S, Kawano Y, Bianchi G, Roccaro AM, Ghobrial IM.

    Cell autonomous and microenvironmental regulation of tumor progression in precursor states of multiple myeloma.

    Curr Opin Hematol. 2016 Jul;23(4):426-33. doi: 10.1097/MOH.0000000000000259. PMID: 27101529.

  17. 92.

    Sugata K, Yasunaga J, Miura M, Akari H, Utsunomiya A, Nosaka K, Watanabe Y, Suzushima H, Koh KR, Nakagawa M, Kohara M, Matsuoka M.

    Enhancement of anti-STLV-1/HTLV-1 immune responses through multimodal effects of anti-CCR4 antibody.

    Sci Rep. 2016 Jun 2;6:27150. doi: 10.1038/srep27150. PMID: 27250643; PMCID: PMC4890010.

  18. 93.

    Higuchi Y, Tokunaga K, Watanabe Y, Kawakita T, Harada N, Yamaguchi S, Nosaka K, Mitsuya H, Asou N.

    Lineage switch with t(6;11)(q27;q23) from T-cell lymphoblastic lymphoma to acute monoblastic leukemia at relapse.

    Cancer Genet. 2016 Jun;209(6):267-71. doi: 10.1016/j.cancergen.2016.05.070. Epub 2016 May 18. PMID: 27268298.

  19. 94.

    Fujiwara S, Mochinaga H, Nakata H, Ohshima K, Matsumoto M, Uchiba M, Mikami Y, Hata H, Okuno Y, Mitsuya H, Nosaka K.

    Successful treatment of TAFRO syndrome, a variant type of multicentric Castleman disease with thrombotic microangiopathy, with anti-IL-6 receptor antibody and steroids.

    Int J Hematol. 2016 Jun;103(6):718-23. doi: 10.1007/s12185-016-1978-2. Epub 2016 Mar 15. PMID: 26980221.

  20. 95.

    Roccaro AM, Sacco A, Shi J, Chiarini M, Perilla-Glen A, Manier S, Glavey S, Aljawai Y, Mishima Y, Kawano Y, Moschetta M, Correll M, Improgo MR, Brown JR, Imberti L, Rossi G, Castillo JJ, Treon SP, Freedman ML, Van Allen EM, Hide W, Hiller E, Rainville I, Ghobrial IM.

    Exome sequencing reveals recurrent germ line variants in patients with familial Waldenström macroglobulinemia.

    Blood. 2016 May 26;127(21):2598-606. doi: 10.1182/blood-2015-11-680199. Epub 2016 Feb 22. PMID: 26903547.

  21. 96.

    Inoue Y, Fuji S, Tanosaki R, Fukuda T.

    Pretransplant mogamulizumab against ATLL might increase the risk of acute GVHD and non-relapse mortality.

    Bone Marrow Transplant. 2016 May;51(5):725-7. doi: 10.1038/bmt.2015.315. Epub 2015 Dec 21. PMID: 26691420.

  22. 97.

    Moschetta M, Mishima Y, Kawano Y, Manier S, Paiva B, Palomera L, Aljawai Y, Calcinotto A, Unitt C, Sahin I, Sacco A, Glavey S, Shi J, Reagan MR, Prosper F, Bellone M, Chesi M, Bergsagel LP, Vacca A, Roccaro AM, Ghobrial IM.

    Targeting vasculogenesis to prevent progression in multiple myeloma.

    Leukemia. 2016 May;30(5):1103-15. doi: 10.1038/leu.2016.3. Epub 2016 Feb 3. PMID: 26859080.

  23. 98.

    Kumamoto H, Fukano M, Nakano T, Iwagami K, Takeyama C, Kohgo S, Imoto S, Amano M, Kuwata-Higashi N, Aoki M, Abe H, Mitsuya H, Fukuhara K, Haraguchi K.

    Diastereoselective Synthesis of 6″-(Z)- and 6″-(E)-Fluoro Analogues of Anti-hepatitis B Virus Agent Entecavir and Its Evaluation of the Activity and Toxicity Profile of the Diastereomers.

    J Org Chem. 2016 Apr 1;81(7):2827-36. doi: 10.1021/acs.joc.6b00105. Epub 2016 Mar 24. PMID: 27009432.

  24. 99.

    Kuriyama K, Fuji S, Inamoto Y, Tajima K, Tanaka T, Inoue Y, Ito R, Hayashi Y, Ito A, Kurosawa S, Kim SW, Yamashita T, Fukuda T.

    Impact of low-dose rabbit anti-thymocyte globulin in unrelated hematopoietic stem cell transplantation.

    Int J Hematol. 2016 Apr;103(4):453-60. doi: 10.1007/s12185-016-1947-9. Epub 2016 Feb 9. PMID: 26857285.

  25. 100.

    Tanaka Y, Kurosawa S, Tajima K, Tanaka T, Ito R, Inoue Y, Okinaka K, Inamoto Y, Fuji S, Kim SW, Tanosaki R, Yamashita T, Fukuda T.

    Analysis of non-relapse mortality and causes of death over 15 years following allogeneic hematopoietic stem cell transplantation.

    Bone Marrow Transplant. 2016 Apr;51(4):553-9. doi: 10.1038/bmt.2015.330. Epub 2016 Jan 11. PMID: 26752142.

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