KUMAMOTO University

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研究実績RESEARCH ACHIEVEMENTS

  1. Bianchi G, Czarnecki PG, Ho M, Roccaro AM, Sacco A, Kawano Y, Gulla A, Samur AA, Chen T, Wen K, Tai YT, Moscvin M, Wu X, Camci-Unal G, Da Via MC, Bolli N, Sewastianik T, Carrasco RD, Ghobrial IM, Anderson KC.

    ROBO1 Promotes Homing, Dissemination, and Survival of Multiple Myeloma within the Bone Marrow Microenvironment.

    Blood Cancer Discovery 2(4):338-353.2021. doi: 10.1158/2643-3230.BCD-20-0164. Epub 2021 Apr 10.

    https://pubmed.ncbi.nlm.nih.gov/34238761/

     

  2. Tanaka T, Nakamae H, Ito A, Fuji S, Hirose A, Eto T, Henzan H, Takase K, Yamasaki S, Makiyama J, Moriuchi Y, Choi I, Nakano N, Hiramoto N, Kato K, Sato T, Sawayama Y, Kim SW, Inoue Y, Inamoto Y, Fukuda T.

    A Phase I/II Multicenter Trial of HLA-Haploidentical PBSCT with PTCy for Aggressive Adult T Cell Leukemia/Lymphoma.

    Transplant Cell Ther 27(11):928 e1-e7,2021.doi: 10.1016/j.jtct.2021.07.010

    https://pubmed.ncbi.nlm.nih.gov/34274491/

  3. Tatetsu H, Tenen DG, Chai L.

    The Interplay between Transcription Factor SALL4 and Histone Modifiers in Hematopoietic Stem and Progenitor Cells.

    J Cell Immunol 3(1):26-30.2021.   doi: 10.33696/immunology.3.073.

    https://pubmed.ncbi.nlm.nih.gov/33884376/

     

  4. Hosen N, Yoshihara S, Takamatsu H, Ri M, Nagata Y, Kosugi H, Shimomura Y, Hanamura I, Fuji S, Minauchi K, Kuroda J, Suzuki R, Nishimura N, Uoshima N, Nakamae H, Kawano Y, Mizuno I, Gomyo H, Suzuki K, Ozaki S, Nakamura S, Imai Y, Kizaki M, Negoro E, Handa H, Iida S.

    Expression of activated integrin β7 in multiple myeloma patients.

    Int J Hematol 114(1):3-7,2021. doi: 10.1007/s12185-021-03162-2.

    https://pubmed.ncbi.nlm.nih.gov/33999338/

     

  5. Hiyoshi M, Takahashi N, Eltalkhawy YM, Noyori O, Lotfi S, Panaampon J, Okada S, Tanaka Y, Ueno T, Fujisawa JI, Sato Y, Suzuki T, Hasegawa H, Tokunaga M, Satou Y, Yasunaga JI, Matsuoka M, Utsunomiya A, Suzu S.

    M-Sec induced by HTLV-1 mediates an efficient viral transmission.

    PLoS Pathog 17(11):e1010126,2021.  doi: 10.1371/journal.ppat.1010126.

    https://pubmed.ncbi.nlm.nih.gov/34843591/

  6. Nosaka K and Matsuoka M

    Adult T-cell leukemia-lymphoma as a viral disease: subtypes based on viral aspects.

    ancer Sci ,112(5):1688-1694. doi: 10.1111/cas.14869. Epub 2021 Mar 30.

    https://pubmed.ncbi.nlm.nih.gov/33630351/

     

     

  7. Sakata K, Kikuchi J, Emoto K, Kotaki T, Ota Y, Nishina N, Hanaoka H, Otomo K, Suzuki K, Kaneko Y, Takeuchi T.

    Refractory IgG4-related Pleural Disease with Chylothorax: A Case Report and Literature Review.

    Intern Med 60(13):2135-2143,2021.doi: 10.2169/internalmedicine.6313-20. Epub 2021 Feb 1.

    https://pubmed.ncbi.nlm.nih.gov/33518567/

     

  8. Inoue Y, Nakano N, Fuji S, Eto T, Kawakita T, Suehiro Y, Miyamoto T, Sawayama Y, Uchida N, Kondo T, Kanda J, Atsuta Y, Fukuda T, Yoshimitsu M, Kato K, ATL Working Group of the Japan Society for Hematopoietic Cell Transplantation.

    Impact of conditioning intensity and regimen on transplant outcomes in patients with adult T-cell leukemia-lymphoma.

    Bone Marrow Transplant 56(12):2964-2974,2021.  doi: 10.1038/s41409-021-01445-0.

    https://pubmed.ncbi.nlm.nih.gov/34462567/

     

  9. Maeda M, Muraki Y, Kosaka T, Yamada T, Aoki Y, Kaku M, Seki M, Tanabe Y, Fujita N, Niki Y, Morita K, Yanagihara K, Yoshida K, Kawaguchi T.

    Impact of health policy on structural requisites for antimicrobial stewardship: A nationwide survey conducted in Japanese hospitals after enforcing the revised reimbursement system for antimicrobial stewardship programs.

    J Infect Chemother 27(1):1-6,2021. doi: 10.1016/j.jiac.2020.09.015.

    https://pubmed.ncbi.nlm.nih.gov/33008739/

     

  10. Ohguchi H, Park PM, Wang T, Gryder BE, Ogiya D, Kurata K, Zhang X, Li D, Pei C, Masuda T, Johansson C, Wimalasena VK, Kim Y, Hino S, Usuki S, Kawano Y, Samur MK, Tai YT, Munshi NC, Matsuoka M, Ohtsuki S, Nakao M, Minami T, Lauberth S, Khan J, Oppermann U, Durbin AD, Anderson KC, Hideshima T, Qi J.

    Lysine Demethylase 5A is Required for MYC Driven Transcription in Multiple Myeloma.

    Blood Cancer Discov 2(4):370-387,2021. doi: 10.1158/2643-3230.BCD-20-0108.

    https://pubmed.ncbi.nlm.nih.gov/34258103/

     

  11. Jang JH, Tomiyama Y, Miyazaki K, Nagafuji K, Usuki K, Uoshima N, Fujisaki T, Kosugi K, Matsumura I, Sasaki K, Kizaki M, Sawa M, Hidaka M, Kobayashi N, Ichikawa S, Yonemura Y, Enokitani K, Matsuda A, Ozawa K, Mitani K, Lee JW, Nakao S.

    Efficacy and safety of romiplostim refractory aplastic anemia: a phase 2/3, multicentre, open-label study.

    Brit J Haematol 192(1):190-199,2021. doi: 10.1111/bjh.17190. Epub 2020 Nov 5.

    https://pubmed.ncbi.nlm.nih.gov/33152120/

     

  12. Kawakita T, Hirano T, Inoue Y, Irie Y, Sugitani H, Kubota A, Watanabe M, Ueno M, Mitsui N, Yamaguchi S, Inoue Y, Sakai T, Harada N, Matsuoka M, Hidaka M.

    Feasibility of an intensified myeloablative conditioning regimen consisting of busulfan, fludarabine, cytarabine, and total body irradiation before single cord blood transplantation in elderly patients.

    Int J Hematol 114(1):85-93,2021. doi: 10.1007/s12185-021-03131-9.

    https://pubmed.ncbi.nlm.nih.gov/33740219/

     

  13. Nozaki K, Maruyama D, Maeshima AM, Tajima K, Itami J, Shichijo T, Yuda S, Suzuki T, Toyoda K, Yamauchi N, Makita S, Fukuhara S, Munakata W, Kobayashi Y, Taniguchi H, Izutsu K and Tobinai K.

    The role of local radiotherapy following rituximab-containing chemotherapy in patients with transformed indolent B-cell lymphoma.

    Eur J Haematol 106(2): 213-220. doi: 10.1111/ejh.13539. Epub 2020 Nov 6.

    https://pubmed.ncbi.nlm.nih.gov/33098704/

     

     

  14. Travis Chia, Tomofumi Nakamura, Masayuki Amano, Nobutoki Takamune, Masao Matsuoka, Hirotomo Nakata

    A small molecule, ACAi-028, with anti-HIV-1 activity targets a novel hydrophobic pocket on HIV-1 capsid

    Antimicrob Agents Chemother. 2021 Jul 6;AAC0103921. doi: 10.1128/AAC.01039-21. Online ahead of print.

    https://pubmed.ncbi.nlm.nih.gov/34228546/

     

  15. Izaki M, Yasunaga JI, Nosaka K, Sugata K, Utsunomiya H, Suehiro Y, Shichijo T, Yamada A, Sugawara Y, Hibi T, Inomata Y, Akari H, Melamed A, Bangham C, Matsuoka M.

    In vivo dynamics and adaptation of HTV-1-infected clones under different clinical conditions

    PLOS Pathogens.2021 Feb 1;17(2):e1009271. doi: 10.1371/journal.ppat.1009271. Online ahead of print .PMID: 33524072

    https://pubmed.ncbi.nlm.nih.gov/33524072/

     

  16. Toyoda K, Yasunaga JI, Choi I, Suehiro Y, Uike N, Okamura J, Matsuoka M.

    The HTLV-1 proviral status is a potential prognostic biomarker for adult T-cell leukemia-lymphoma treated with allogeneic stem cell transplantation.

    Bone Marrow Transplant 56(8):2027-2030,2021. doi: 10.1038/s41409-021-01311-z.

    https://pubmed.ncbi.nlm.nih.gov/33927348/

     

  17. Ohmachi K, Kinoshita T, Tobinai K, Ogawa G, Mizutani T, Yamauchi N, Fukuhara N, Uchida T, Yamamoto K, Miyazaki K, Tsukamoto N, Iida S, Utsumi T, Yoshida I, Imaizumi Y, Tokunaga T, Yoshida S, Masaki Y, Murayama T, Yakushijin Y, Suehiyo Y, Nosaka K, Dobashi N, Kuroda J, Takamatsu Y, Maruyama D, Ando K, Ishizawa K, Ogura M, Yoshino T, Hotta T, Tsukasaki K, Nagai H Japan Clinical Oncology Group.

    A randomized phase 2/3 study of R-CHOP vs CHOP combined with dose-dense rituximab for DLBCL: the JCOG0601 trial.

    Blood Adv 5(4):984-993,2021. doi: 10.1182/bloodadvances.2020002567.

    https://pubmed.ncbi.nlm.nih.gov/33591324/

     

  18. Hosokawa K, Ishiyama K, Ikemoto T, Sugimori C, Noji H, Shichishima T, Obara N, Chiba S, Ninomiya H, Nguyen M.A.T, Shirasugi Y, Nakamura Y, Ando K, Ueda Y, Yonemura Y, Kawaguchi T, Nishimura J, Kanakura Y, Nakao S.

    The clinical significance of PNH-phenotype cells accounting for < 0.01% of total granulocytes detected by the Clinical and Laboratory Standards Institute methods in patients with bone marrow failure.

    Ann Hematol 100(8):1975-82,2021. doi: 10.1007/s00277-020-04314-w

    https://pubmed.ncbi.nlm.nih.gov/33095337/

     

     

     

  19. Penova M, Kawaguchi S, Yasunaga JI, Kawaguchi T, Sato T, Takahashi M, Shimizu M, Saito M, Tsukasaki K, Nakagawa M, Takenouchi N, Hara H, Matsuura E, Nozuma S, Takashima H, Izumo S, Watanabe T, Uchimaru K, Iwanaga M, Utsunomiya A, Tabara Y, Paul R, Yamano Y, Matsuoka M and Matsuda F.

    HTLV-1 associated myelopathy/tropical spastic paraparesis in the Japanese population – a genome-wide association study.

     Proc Natl Acad Sci USA 118(11):e2004199118. doi: 10.1073/pnas.2004199118.

    https://pubmed.ncbi.nlm.nih.gov/33649182/

     

  20. Ono A, Kitano Y, Imai K, Matsumoto T, Endo S, Tokunaga K, Hayashi H, Yamashita YI, Matsuoka M, Baba H.

    A case of primary nonleukemic myeloid sarcoma of the spleen, successfully treated by surgery and hematopoietic stem cell transplantation.

    Surg Case Rep 7(1):180,2021. doi: 10.1186/s40792-021-01257-w.

    https://pubmed.ncbi.nlm.nih.gov/34379239/

     

  21. Huang J, Gou H, Yao J, Yi K, Jin Z, Matsuoka M and Zhao T

    The noncanonical role of EZH2 in cancer.

    Cancer Sci 112(4):1376-1382. doi: 10.1111/cas.14840. Epub 2021 Feb 24.

    https://pubmed.ncbi.nlm.nih.gov/33615636/

     

  22. Izutsu K, Ando K, Nishikori M, Shibayama H, Teshima T, Kuroda J, Kato K, Imaizumi Y, Nosaka K, Sakai R, Hojo S, Nakanishi T, Rai S.

    Phase II study of tazemetostat for relapsed or refractory B-cell non-Hodgkin lymphoma with EZH2 mutation in Japan.

    Cancer Sci 112(9):3627-3635,2021. doi: 10.1111/cas.15040.

    https://pubmed.ncbi.nlm.nih.gov/34159682/

     

  23. Ishihara A, Yamauchi T, Ikeda K, Fukuyoshi Y, Yokoyama T, Yonemura Y, Uchiba M, Matsui H.

    Glycosylated ferritin as an improved marker for post-transfusion iron overload.

    Int J Hematol 113(4): 537-546,2021. doi: 10.1007/s12185-020-03056-9. Epub 2021 Jan 5.

    https://pubmed.ncbi.nlm.nih.gov/33400141/

     

  24. Inoue Y, Okinaka K, Fuji S, Inamoto Y, Uchida N, Toya T, Ikegame K, Eto T, Ozawa Y, Iwato K, Kanda Y, Atsuta Y, Ogata M, Fukuda T, Transplant Complications Working Group of The Japan Society for Hematopoietic Cell Transplantation.

    Severe acute graft-versus-host disease increases the incidence of blood stream infection and mortality after allogeneic hematopoietic cell transplantation: Japanese transplant registry study.

    Bone Marrow Transplant 56(9):2125-36,2021.  doi: 10.1038/s41409-021-01291-0.

    https://pubmed.ncbi.nlm.nih.gov/33875815/

     

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