KUMAMOTO University

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研究実績RESEARCH ACHIEVEMENTS

  1. Jang JH, Tomiyama Y, Miyazaki K, Nagafuji K, Usuki K, Uoshima N, Fujisaki T, Kosugi K, Matsumura I, Sasaki K, Kizaki M, Sawa M, Hidaka M, Kobayashi N, Ichikawa S, Yonemura Y, Enokitani K, Matsuda A, Ozawa K, Mitani K, Lee JW, Nakao S.

    Efficacy and safety of romiplostim refractory aplastic anemia: a phase 2/3, multicentre, open-label study.

    Brit J Haematol 192(1):190-199,2021. doi: 10.1111/bjh.17190. Epub 2020 Nov 5.

    https://pubmed.ncbi.nlm.nih.gov/33152120/

     

  2. Ono A, Kitano Y, Imai K, Matsumoto T, Endo S, Tokunaga K, Hayashi H, Yamashita YI, Matsuoka M, Baba H.

    A case of primary nonleukemic myeloid sarcoma of the spleen, successfully treated by surgery and hematopoietic stem cell transplantation.

    Surg Case Rep 7(1):180,2021. doi: 10.1186/s40792-021-01257-w.

    https://pubmed.ncbi.nlm.nih.gov/34379239/

     

  3. Ishihara A, Yamauchi T, Ikeda K, Fukuyoshi Y, Yokoyama T, Yonemura Y, Uchiba M, Matsui H.

    Glycosylated ferritin as an improved marker for post-transfusion iron overload.

    Int J Hematol 113(4): 537-546,2021. doi: 10.1007/s12185-020-03056-9. Epub 2021 Jan 5.

    https://pubmed.ncbi.nlm.nih.gov/33400141/

     

  4. Inoue Y, Okinaka K, Fuji S, Inamoto Y, Uchida N, Toya T, Ikegame K, Eto T, Ozawa Y, Iwato K, Kanda Y, Atsuta Y, Ogata M, Fukuda T, Transplant Complications Working Group of The Japan Society for Hematopoietic Cell Transplantation.

    Severe acute graft-versus-host disease increases the incidence of blood stream infection and mortality after allogeneic hematopoietic cell transplantation: Japanese transplant registry study.

    Bone Marrow Transplant 56(9):2125-36,2021.  doi: 10.1038/s41409-021-01291-0.

    https://pubmed.ncbi.nlm.nih.gov/33875815/

     

  5. Ma G, Yasunaga JI, Shimura K,  Takemoto K, Watanabe M, Amano M, Nakata H, Liu B, Zuo X, and Matsuoka M.

    Human retroviral antisense mRNAs are retained in the nuclei of infected cells for viral persistence

    Proc Natl Acad Sci U S A.118(17):e2014783118,2021. doi: 10.1073/pnas.2014783118.

    https://pubmed.ncbi.nlm.nih.gov/33875584/

     

     

  6. Sakata K, Kikuchi J, Emoto K, Kotaki T, Ota Y, Nishina N, Hanaoka H, Otomo K, Suzuki K, Kaneko Y, Takeuchi T.

    Refractory IgG4-related Pleural Disease with Chylothorax: A Case Report and Literature Review.

    Intern Med 60(13):2135-2143,2021.doi: 10.2169/internalmedicine.6313-20. Epub 2021 Feb 1.

    https://pubmed.ncbi.nlm.nih.gov/33518567/

     

  7. Kawakita T, Hirano T, Inoue Y, Irie Y, Sugitani H, Kubota A, Watanabe M, Ueno M, Mitsui N, Yamaguchi S, Inoue Y, Sakai T, Harada N, Matsuoka M, Hidaka M.

    Feasibility of an intensified myeloablative conditioning regimen consisting of busulfan, fludarabine, cytarabine, and total body irradiation before single cord blood transplantation in elderly patients.

    Int J Hematol 114(1):85-93,2021. doi: 10.1007/s12185-021-03131-9.

    https://pubmed.ncbi.nlm.nih.gov/33740219/

     

  8. Hiyoshi M, Takahashi N, Eltalkhawy YM, Noyori O, Lotfi S, Panaampon J, Okada S, Tanaka Y, Ueno T, Fujisawa JI, Sato Y, Suzuki T, Hasegawa H, Tokunaga M, Satou Y, Yasunaga JI, Matsuoka M, Utsunomiya A, Suzu S.

    M-Sec induced by HTLV-1 mediates an efficient viral transmission.

    PLoS Pathog 17(11):e1010126,2021.  doi: 10.1371/journal.ppat.1010126.

    https://pubmed.ncbi.nlm.nih.gov/34843591/

  9. Kenji Maeda, Masayuki Amano, Yukari Uemura, Kiyoto Tsuchiya, Tomoko Matsushima, Kenta Noda, Yosuke Shimizu, Asuka Fujiwara, Yuki Takamatsu, Yasuko Ichikawa, Hidehiro Nishimura, Mari Kinoshita, Shota Matsumoto, Hiroyuki Gatanaga, Kazuhisa Yoshimura, Shin-Ichi Oka, Ayako Mikami, Wataru Sugiura, Toshiyuki Sato, Tomokazu Yoshida, Shinya Shimada, Hiroaki Mitsuya.

    Correlates of neutralizing/SARS-CoV-2-S1-binding antibody response with adverse effects and immune kinetics in BNT162b2-vaccinated individuals.

    Sci Rep. 2021 Nov 24;11(1):22848. doi: 10.1038/s41598-021-01930-y.

    https://pubmed.ncbi.nlm.nih.gov/34819514/

     

  10. Uekawa K, Kaku Y, Amadatsu T, Matsuzaki H, Ohmori Y, Kawano T, Hirata S, Yamaguchi T, Kosho T. & Mukasa A.

    Intracranial and extracranial multiple arterial dissecting aneurysms in rheumatoid arthritis: A case report.

    Interv Neuroradiol 27(2):212-218,2021. doi: 10.1177/1591019920965359.

    https://pubmed.ncbi.nlm.nih.gov/33076745/

     

  11. Inoue Y, Nakano N, Fuji S, Eto T, Kawakita T, Suehiro Y, Miyamoto T, Sawayama Y, Uchida N, Kondo T, Kanda J, Atsuta Y, Fukuda T, Yoshimitsu M, Kato K, ATL Working Group of the Japan Society for Hematopoietic Cell Transplantation.

    Impact of conditioning intensity and regimen on transplant outcomes in patients with adult T-cell leukemia-lymphoma.

    Bone Marrow Transplant 56(12):2964-2974,2021.  doi: 10.1038/s41409-021-01445-0.

    https://pubmed.ncbi.nlm.nih.gov/34462567/

     

  12. Tanaka T, Nakamae H, Ito A, Fuji S, Hirose A, Eto T, Henzan H, Takase K, Yamasaki S, Makiyama J, Moriuchi Y, Choi I, Nakano N, Hiramoto N, Kato K, Sato T, Sawayama Y, Kim SW, Inoue Y, Inamoto Y, Fukuda T.

    A Phase I/II Multicenter Trial of HLA-Haploidentical PBSCT with PTCy for Aggressive Adult T Cell Leukemia/Lymphoma.

    Transplant Cell Ther 27(11):928 e1-e7,2021.doi: 10.1016/j.jtct.2021.07.010

    https://pubmed.ncbi.nlm.nih.gov/34274491/

  13. Penova M, Kawaguchi S, Yasunaga JI, Kawaguchi T, Sato T, Takahashi M, Shimizu M, Saito M, Tsukasaki K, Nakagawa M, Takenouchi N, Hara H, Matsuura E, Nozuma S, Takashima H, Izumo S, Watanabe T, Uchimaru K, Iwanaga M, Utsunomiya A, Tabara Y, Paul R, Yamano Y, Matsuoka M and Matsuda F.

    HTLV-1 associated myelopathy/tropical spastic paraparesis in the Japanese population – a genome-wide association study.

     Proc Natl Acad Sci USA 118(11):e2004199118. doi: 10.1073/pnas.2004199118.

    https://pubmed.ncbi.nlm.nih.gov/33649182/

     

  14. Ito A, Nakano N, Tanaka T, Fuji S, Makiyama J, Inoue Y, Choi I, Nakamae H, Nagafuji K, Takase K, Machida S, Takahashi T, Sawayama Y, Kamimura T, Kato K, Kawakita T, Ogata M, Sakai R, Shiratori S, Uchimaru K, Inamoto Y, Utsunomiya A, Fukuda T.

    Improved survival of patients with aggressive ATL by increased use of allo-HCT: a prospective observational study.

    Blood Adv 5(20):4156-66,2021. doi: 10.1182/bloodadvances.2021004932.

    https://pubmed.ncbi.nlm.nih.gov/34500464/

  15. Nosaka K and Matsuoka M

    Adult T-cell leukemia-lymphoma as a viral disease: subtypes based on viral aspects.

    ancer Sci ,112(5):1688-1694. doi: 10.1111/cas.14869. Epub 2021 Mar 30.

    https://pubmed.ncbi.nlm.nih.gov/33630351/

     

     

  16. Ito S, Iwanaga M, Nosaka K, Imaizumi Y, Ishitsuka K, Amano M, Utsunomiya A, Tokura Y, Watanabe T, Uchimaru K, Tsukasaki K, Collaborative Investigators.

    Epidemiology of adult T-cell leukemia-lymphoma in Japan: An updated analysis, 2012-2013.

    Cancer Sci 112(10):4346-4354,2021. doi: 10.1111/cas.15097.

    https://pubmed.ncbi.nlm.nih.gov/34355480/

     

  17. Huang J, Gou H, Yao J, Yi K, Jin Z, Matsuoka M and Zhao T

    The noncanonical role of EZH2 in cancer.

    Cancer Sci 112(4):1376-1382. doi: 10.1111/cas.14840. Epub 2021 Feb 24.

    https://pubmed.ncbi.nlm.nih.gov/33615636/

     

  18. Bellon M, Bialuk I, Galli V, Bai XT, Farre L, Bittencourt A, Marçais A, Petrus MN, Ratner L, Waldmann TA, Asnafi V, Gessain A, Matsuoka M, Franchini G, Hermine O, Watanabe T, Nicot C.

    Germinal epimutation of Fragile Histidine Triad (FHIT) gene is associated with progression to acute and chronic adult T-cell leukemia diseases.

    Mol Cancer 20(1):86,2021.  doi: 10.1186/s12943-021-01370-2.

    https://pubmed.ncbi.nlm.nih.gov/34092254/

     

  19. Travis Chia, Tomofumi Nakamura, Masayuki Amano, Nobutoki Takamune, Masao Matsuoka, Hirotomo Nakata

    A small molecule, ACAi-028, with anti-HIV-1 activity targets a novel hydrophobic pocket on HIV-1 capsid

    Antimicrob Agents Chemother. 2021 Jul 6;AAC0103921. doi: 10.1128/AAC.01039-21. Online ahead of print.

    https://pubmed.ncbi.nlm.nih.gov/34228546/

     

  20. Toyoda K, Yasunaga JI, Choi I, Suehiro Y, Uike N, Okamura J, Matsuoka M.

    The HTLV-1 proviral status is a potential prognostic biomarker for adult T-cell leukemia-lymphoma treated with allogeneic stem cell transplantation.

    Bone Marrow Transplant 56(8):2027-2030,2021. doi: 10.1038/s41409-021-01311-z.

    https://pubmed.ncbi.nlm.nih.gov/33927348/

     

  21. Izaki M, Yasunaga JI, Nosaka K, Sugata K, Utsunomiya H, Suehiro Y, Shichijo T, Yamada A, Sugawara Y, Hibi T, Inomata Y, Akari H, Melamed A, Bangham C, Matsuoka M.

    In vivo dynamics and adaptation of HTV-1-infected clones under different clinical conditions

    PLOS Pathogens.2021 Feb 1;17(2):e1009271. doi: 10.1371/journal.ppat.1009271. Online ahead of print .PMID: 33524072

    https://pubmed.ncbi.nlm.nih.gov/33524072/

     

  22. Hosokawa K, Ishiyama K, Ikemoto T, Sugimori C, Noji H, Shichishima T, Obara N, Chiba S, Ninomiya H, Nguyen M.A.T, Shirasugi Y, Nakamura Y, Ando K, Ueda Y, Yonemura Y, Kawaguchi T, Nishimura J, Kanakura Y, Nakao S.

    The clinical significance of PNH-phenotype cells accounting for < 0.01% of total granulocytes detected by the Clinical and Laboratory Standards Institute methods in patients with bone marrow failure.

    Ann Hematol 100(8):1975-82,2021. doi: 10.1007/s00277-020-04314-w

    https://pubmed.ncbi.nlm.nih.gov/33095337/

     

     

     

  23. Nozaki K, Maruyama D, Maeshima AM, Tajima K, Itami J, Shichijo T, Yuda S, Suzuki T, Toyoda K, Yamauchi N, Makita S, Fukuhara S, Munakata W, Kobayashi Y, Taniguchi H, Izutsu K and Tobinai K.

    The role of local radiotherapy following rituximab-containing chemotherapy in patients with transformed indolent B-cell lymphoma.

    Eur J Haematol 106(2): 213-220. doi: 10.1111/ejh.13539. Epub 2020 Nov 6.

    https://pubmed.ncbi.nlm.nih.gov/33098704/

     

     

  24. Abdallah MG, Niibori-Nambu A, Morii M, Yokomizo T, Yokomizo T, Ideue T, Kubota S, Teoh VSI, Mok MMH, Wang CQ, Omar AA, Tokunaga K, Iwanaga E, Matsuoka M, Asou N, Nakagata N, Araki K, AboElenin M, Madboly SH, Sashida G, Osato M.

    RUNX1-ETO (RUNX1-RUNX1T1) induces myeloid leukemia in mice in an age-dependent manner.

    Leukemia 35(10):2983-2988,2021. doi: 10.1038/s41375-021-01268-4

    https://pubmed.ncbi.nlm.nih.gov/34148054/

     

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